Subject: Biology | Level: GCSE | Exam Board: Edexcel
Master the incredible systems that keep your body alive and functioning. This topic covers the nervous and endocrine systems, and how homeostasis maintains your internal environment—essential knowledge that guarantees marks in every GCSE Biology paper.
Revision Notes & Key Concepts
Key Terms & Definitions
- Homeostasis
- The regulation of the internal conditions of a cell or organism to maintain optimum conditions for function, in response to internal and external changes.
- Negative Feedback
- A control mechanism that reacts to a change in a condition by trying to bring the condition back to a normal level.
- Synapse
- The junction between two neurones where chemicals (neurotransmitters) diffuse across the gap to transmit the signal.
- Hormone
- A chemical messenger secreted by an endocrine gland directly into the bloodstream, which produces an effect on target organs.
- Reflex Action
- A rapid, automatic response to a stimulus that does not involve the conscious part of the brain.
- Type 1 Diabetes
- A disorder in which the pancreas fails to produce sufficient insulin, leading to uncontrolled high blood glucose levels.
Worked Examples
Worked Example
Question: Describe how the body regulates blood glucose concentration if it falls too low. (4 marks)
Solution: Step 1: Identify the stimulus and receptor. The pancreas detects the low blood glucose concentration. Step 2: Identify the hormone released. The pancreas secretes the hormone glucagon into the blood. Step 3: Identify the target organ and the action. Glucagon travels to the liver. Step 4: Describe the specific chemical change. It causes the liver to break down stored glycogen into glucose, which is released into the blood, raising the concentration back to normal.
Worked Example
Question: Compare the nervous and endocrine systems. (6 marks)
Solution: Step 1: Compare the type of signal. The nervous system uses electrical impulses, whereas the endocrine system uses chemical messengers (hormones). Step 2: Compare the method of transmission. Nervous signals travel along neurones, while hormones travel in the bloodstream. Step 3: Compare the speed of response. The nervous response is very fast (milliseconds), whereas the endocrine response is slower. Step 4: Compare the duration of the effect. The effect of a nervous impulse is short-lived, but the effect of a hormone is long-lasting. Step 5: Compare the target area. Nervous impulses act on a very specific target (a single muscle or gland), while hormones can have widespread effects on multiple target organs.
Worked Example
Question: A student has a mass of 85 kg and a height of 1.75 m. Calculate their BMI and state whether they are considered obese. (3 marks)
Solution: Step 1: State the formula. BMI = mass / height² Step 2: Substitute the values. BMI = 85 / (1.75)² Step 3: Calculate the result. 85 / 3.0625 = 27.75... = 27.8 (to 1 d.p.) Step 4: Make a conclusion. The BMI is 27.8. As this is below 30, the student is overweight but not considered obese.
Practice Questions
Question: State the function of a receptor. (1 mark)
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Question: Explain how information passes across a synapse. (3 marks)
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Question: A person with Type 1 diabetes has high blood glucose concentration after eating a meal. Explain why. (3 marks)
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Question: Describe the role of the skin in regulating body temperature when the environment is very cold. (4 marks)
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Question: Evaluate the use of BMI versus waist:hip ratio as a measure of obesity. (4 marks)
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