AQA · A-Level · Biology

    Course version: 7402 · Version from Sept 2016

    Prokaryotic cells are much smaller than eukaryotic cells. They also differ…

    Full specification wording

    Structure of prokaryotic cells and of viruses: Prokaryotic cells are much smaller than eukaryotic cells. They also differ from eukaryotic cells in having: cytoplasm that lacks membrane-bound organelles smaller ribosomes no nucleus; instead they have a single circular DNA molecule that is free in the cytoplasm and is not associated with proteins a cell wall that contains murein, a glycoprotein.

    Prokaryotes are typically 0.5-5 micrometres across against 10-100 micrometres for a eukaryotic cell, and the differences are not just of scale.

    Checked against the AQA 7402 specification (opens in a new tab) on .

    • Point 1 of 3
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Prokaryotes are typically 0.5-5 micrometres across against 10-100 micrometres for a eukaryotic cell, and the differences are not just of scale. Prokaryotic cytoplasm contains no membrane-bound organelles at all: no nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus or chloroplasts, so respiratory enzymes are located on the cell-surface membrane instead. Its ribosomes are smaller, 70S rather than the 80S of eukaryotes. Its genetic material is one circular DNA molecule lying free in the cytoplasm as a nucleoid, not wound around histone proteins and not enclosed by a nuclear envelope, whereas a eukaryote has several linear chromosomes associated with histones inside a nucleus.

    What earns the marks

    • Giving features true of all prokaryotes, for example no membrane-bound organelles and murein in the cell wall.
    • A single circular DNA molecule free in the cytoplasm, with nucleoid accepted, and not associated with proteins or histones.
    • Smaller ribosomes, with 70S accepted as the alternative wording.
    • A cell wall containing murein, with peptidoglycan accepted.
    • The contrast with eukaryotes, whose linear DNA is enclosed in a nucleus and associated with histones.

    Common mistakes and how to put them right

    • Offering a plasmid, a capsule or a flagellum as a feature of all prokaryotic cells, which is incorrect because only some prokaryotes have them.

    • Writing nucleosome instead of nucleoid, or calling the circular DNA a eukaryotic chromosome.

    • Saying prokaryotes have no ribosomes rather than smaller (70S) ribosomes.

    • Describing the prokaryotic cell wall as cellulose or chitin instead of murein.

    • Writing no organelles unqualified, when the credited point is no membrane-bound organelles.

    Exam tips

    • If the question says features of all prokaryotic cells, cross out anything only some of them have before you write: plasmid, capsule and flagellum are incorrect here.
    • Ensure you explicitly state 'membrane-bound' when discussing the lack of organelles in prokaryotes.
    • Use the specification's own words, murein and 70S ribosomes, rather than paraphrases like tough wall or small ribosomes.

    Try the lesson

    The start of the Structure of prokaryotic cells and of viruses: Prokaryotic cells are much smaller than eukaryotic cells. They also differ from eukaryotic cells in having: cytoplasm that lacks membrane-bound organelles smaller ribosomes no nucleus; instead they have a single circular DNA molecule that is free in the cytoplasm and is not associated with proteins a cell wall that contains murein, a glycoprotein. lesson, made from checked teaching notes for this specification point.

    Have a go first

    Which statement correctly describes the structure of a prokaryotic cell?

    Listen

    Prokaryotes are typically 0.5-5 micrometres across against 10-100 micrometres for a eukaryotic cell, and the differences are not just of scale. Prokaryotic cytoplasm contains no membrane-bound organelles at all: no nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus or chloroplasts, so respiratory enzymes are located on the cell-surface membrane instead. Its ribosomes are smaller, 70S rather than the 80S of eukaryotes. Its genetic material is one circular DNA molecule lying free in the cytoplasm as a nucleoid, not wound around histone proteins and not enclosed by a nuclear envelope, whereas a eukaryote has several linear chromosomes associated with histones inside a nucleus. A strong answer earns marks for these points. giving features true of all prokaryotes, for example no membrane-bound organelles and murein in the cell wall. a single circular DNA molecule free in the cytoplasm, with nucleoid accepted, and not associated with proteins or histones. smaller ribosomes, with 70S accepted as the alternative wording. a cell wall containing murein, with peptidoglycan accepted. Exam tip: If the question says features of all prokaryotic cells, cross out anything only some of them have before you write: plasmid, capsule and flagellum are incorrect here.

    See it

    A flowchart with a top node labelled 'Prokaryotic cell' branching to four features. The first branch reads 'Cytoplasm lacks membrane-bound organelles'. The second reads 'Smaller ribosomes'. The third reads 'No nucleus' and leads to a further node, 'Single circular DNA molecule free in the cytoplasm', which leads to 'Not associated with proteins'. The fourth branch reads 'Cell wall contains murein'.
    It shows the features that distinguish a prokaryotic cell from a eukaryotic cell.

    Key words

    Say what each word means before you turn the card.

    circular DNA and nucleoid

    Try answering aloud or in your head before turning the card.

    murein cell wall

    Try answering aloud or in your head before turning the card.

    70S ribosomes

    Try answering aloud or in your head before turning the card.

    no membrane-bound organelles

    Try answering aloud or in your head before turning the card.

    See every definition
    circular DNA and nucleoid
    A single circular DNA molecule that is free in the cytoplasm and is not associated with proteins, lying as a nucleoid.
    murein cell wall
    A cell wall that contains murein, a glycoprotein.
    70S ribosomes
    Smaller ribosomes than those of eukaryotes, which are 80S.
    no membrane-bound organelles
    Cytoplasm that lacks membrane-bound organelles, so respiratory enzymes are located on the cell-surface membrane instead.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A flowchart with a top node labelled 'Prokaryotic cell' branching to four features. The first branch reads 'Cytoplasm lacks membrane-bound organelles'. The second reads 'Smaller ribosomes'. The third reads 'No nucleus' and leads to a further node, 'Single circular DNA molecule free in the cytoplasm', which leads to 'Not associated with proteins'. The fourth branch reads 'Cell wall contains murein'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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