AQA · GCSE · Combined Science

    Course version: 8464 · Version from Sept 2018

    Health issues: Immune reactions initially caused by a pathogen can trigger allergies such as skin rashes and asthma.

    The immune system defends the body against pathogens, but sometimes these reactions have unintended consequences.

      Study notes

      From the checked teaching notes for this specification point.

      The idea

      The immune system defends the body against pathogens, but sometimes these reactions have unintended consequences. An immune reaction initially caused by a pathogen can trigger allergies. After the body responds to an infection, the immune system may become overly sensitive and react to harmless substances in the environment. This inappropriate immune response can lead to allergic conditions like skin rashes or asthma. For example, a person might develop asthma, where their airways become inflamed, following a severe respiratory infection. Understanding this link highlights how diseases can interact and how an immune response to a pathogen can lead to non-communicable health issues.

      What earns the marks

      • State that an immune reaction initially caused by a pathogen can trigger allergies.
      • Identify skin rashes and asthma as examples of allergies triggered by such immune reactions.
      • Explain that this is an example of how different types of diseases (communicable and non-communicable) can interact.
      • Describe asthma as a condition affecting the airways, which can be triggered by an overactive immune response following an infection.

      Common mistakes and how to put them right

      • Believing that allergies are directly caused by the pathogen itself.

        Put it right: The allergy is caused by the immune system's overreaction, which was initially triggered by the pathogen.

      • Confusing communicable and non-communicable diseases.

        Put it right: While the initial pathogen causes a communicable disease, the resulting allergy (like asthma) is non-communicable.

      • Thinking asthma is an infection.

        Put it right: Asthma is an allergic reaction that affects the airways, even though it may be triggered by a prior immune response to an infection.

      Exam tips

      • When asked about disease interactions, use the specific example that an immune reaction to a pathogen can trigger allergies like asthma or skin rashes.
      • Clearly distinguish between the initial infection (caused by a pathogen) and the subsequent allergy (caused by the immune system).

      Try the lesson

      The start of the Health issues: Immune reactions initially caused by a pathogen can trigger allergies such as skin rashes and asthma. lesson, made from checked teaching notes for this specification point.

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      Which condition can be triggered by an immune reaction that was initially caused by a pathogen?

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