AQA · GCSE · Combined Science

    Course version: 8464 · Version from Sept 2018

    The use of hormones to treat infertility (HT only): The fertilised eggs develop into embryos.

    In fertility treatment, eggs are collected from the mother and fertilised outside the body.

    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    In fertility treatment, eggs are collected from the mother and fertilised outside the body. Each fertilised egg, now a single cell called a zygote, divides by mitosis to form a small group of identical cells. This early stage is an embryo. The word 'develop' covers this cell division and the gradual formation of a ball of cells, not just one division. For example, a zygote divides into 2 cells, then 4, then 8, forming a tiny ball within a few days. Only healthy-looking embryos are chosen for the next step. Understanding this stage explains why treatment must be timed carefully and why several embryos may be produced. Note that IVF and infertility treatments are Higher Tier only content.

    What earns the marks

    • A fertilised egg is a single cell formed when a sperm nucleus fuses with an egg nucleus.
    • The fertilised egg divides by mitosis to produce genetically identical cells.
    • Repeated division produces a small ball of cells called an embryo.
    • Development happens outside the mother's body in this fertility treatment.
    • Several fertilised eggs may develop, giving more than one embryo.

    Common mistakes and how to put them right

    • Saying the embryo forms immediately at fertilisation.

      Put it right by stating that the fertilised egg must first divide by mitosis to become an embryo.

    • Confusing an embryo with a fetus.

      Put it right by noting that an embryo is the early ball of cells, while a fetus is a much later stage.

    • Writing that the egg develops into an embryo without fertilisation.

      Put it right by stating that fertilisation by a sperm is needed first.

    Exam tips

    • Use the sequence fertilisation, mitosis, ball of cells, embryo in your answer.
    • Link the word 'develop' to cell division, not to growth in size alone.

    Try the lesson

    The start of the The use of hormones to treat infertility (HT only): The fertilised eggs develop into embryos. lesson, made from checked teaching notes for this specification point.

    Have a go first

    In fertility treatment, what do fertilised eggs develop into?

    Listen

    In fertility treatment, eggs are collected from the mother and fertilised outside the body. Each fertilised egg, now a single cell called a zygote, divides by mitosis to form a small group of identical cells. This early stage is an embryo. The word 'develop' covers this cell division and the gradual formation of a ball of cells, not just one division. For example, a zygote divides into 2 cells, then 4, then 8, forming a tiny ball within a few days. Only healthy-looking embryos are chosen for the next step. Understanding this stage explains why treatment must be timed carefully and why several embryos may be produced. Note that IVF and infertility treatments are Higher Tier only content. A strong answer earns marks for these points. A fertilised egg is a single cell formed when a sperm nucleus fuses with an egg nucleus. The fertilised egg divides by mitosis to produce genetically identical cells. Repeated division produces a small ball of cells called an embryo. Development happens outside the mother's body in this fertility treatment. A common slip: Saying the embryo forms immediately at fertilisation. Instead, stating that the fertilised egg must first divide by mitosis to become an embryo. Exam tip: Use the sequence fertilisation, mitosis, ball of cells, embryo in your answer.

    See it

    A flowchart running from top to bottom. The first box is labelled 'Fertilised egg' and an arrow leads down to a box labelled 'Divides by mitosis'. An arrow leads from that to a box labelled 'Repeated division', then to a box labelled 'Small ball of cells', and finally to a box labelled 'Embryo'. This shows that the fertilised egg divides by mitosis, and repeated division produces a small ball of cells called an embryo.
    It shows the sequence from a fertilised egg dividing by mitosis to form a small ball of cells called an embryo.

    Put it in order

    Put these steps in the order they happen.

    1. 1. Divides by mitosis
    2. 2. Repeated division
    3. 3. Small ball of cells
    4. 4. Embryo
    5. 5. Fertilised egg

    Key words

    Say what each word means before you turn the card.

    Fertilisation

    Try answering aloud or in your head before turning the card.

    Cell division by mitosis

    Try answering aloud or in your head before turning the card.

    Embryo development

    Try answering aloud or in your head before turning the card.

    Infertility treatment

    Try answering aloud or in your head before turning the card.

    See every definition
    Fertilisation
    The process in which a sperm nucleus fuses with an egg nucleus to form a fertilised egg, which is a single cell.
    Cell division by mitosis
    The process by which the fertilised egg divides to produce genetically identical cells.
    Embryo development
    Repeated division produces a small ball of cells, and the word 'develop' covers this cell division and the gradual formation of a ball of cells.
    Infertility treatment
    A treatment in which eggs are collected from the mother and fertilised outside the body, and several fertilised eggs may develop.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 2 boxes numbered instead of named. A flowchart running from top to bottom. The first box is labelled 'Fertilised egg' and an arrow leads down to a box labelled 'Divides by mitosis'. An arrow leads from that to a box labelled 'Repeated division', then to a box labelled 'Small ball of cells', and finally to a box labelled 'Embryo'. This shows that the fertilised egg divides by mitosis, and repeated division produces a small ball of cells called an embryo.
    • 1Box 1

    • 2Box 2

    0 of 2 labelled

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