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    Edexcel A-Level Biology B

    Explore your course, one topic at a time.

    Course overview

    The PEARSON-EDEXCEL A-Level Biology B specification covers 11 study areas with 264 learning objectives (9BI0). Use the topic browser below to explore subtopics, exam tips, common mistakes, and key terminology for each area of the course.

    • 11 study areas
    • 264 learning objectives

    Verified courseQuestions and notes checked against the official specification.

    201
    verified practice questions
    78
    verified teaching notes
    11
    topics

    Your exams

    • Paper 1: Advanced Biochemistry, Microbiology and GeneticsMonday, 7 June 2027, PM
    • Paper 2: Advanced Physiology, Evolution and EcologyMonday, 14 June 2027, PM
    • Paper 3: General and Practical Principles in BiologyFriday, 18 June 2027, AM

    Always confirm dates and times with your exam centre.

    Papers on this course
    PaperTimeMarksWeight
    Paper 1: Advanced Biochemistry, Microbiology and Genetics105 min9030%
    Paper 2: Advanced Physiology, Evolution and Ecology105 min9030%
    Paper 3: General and Practical Principles in Biology150 min12040%

    Explore your topics

    11 study areas

    Biological Molecules2 topics
    Cells, Viruses and Reproduction of Living Things2 topics
    Classification and Biodiversity1 topic
    Exchange and Transport2 topics
    Energy for Biological Processes2 topics
    Microbiology and Pathogens2 topics
    Modern Genetics1 topic
    Origins of Genetic Variation1 topic
    Control Systems2 topics
    Ecosystems2 topics
    Science Practical Endorsement14 topics
    Assessment Objectives1 topic
    About this course

    About Pearson Edexcel A-Level Biology B

    Pearson Edexcel A-Level Biology B is a concept-led course that explores the fundamental principles of biology through a systems-based approach. You will study topics ranging from the molecular building blocks of life to the complex interactions within ecosystems, with a strong emphasis on how biological processes work together to maintain life. The specification is structured into ten topics, each building on core themes such as energy transfer, information flow, and homeostasis.

    The course encourages you to think like a scientist, developing your ability to design experiments, analyse data, and evaluate evidence. Practical skills are integrated throughout, and you will complete a minimum of twelve core practical activities that prepare you for the written exams and a practical endorsement. The specification also highlights the relevance of biology to modern society, including applications in medicine, biotechnology, and environmental management.

    Assessment Structure

    This qualification is assessed through three written exam papers, all taken at the end of the two-year course. Paper 1 covers topics 1-5 and includes a mix of multiple-choice, short-answer, and extended-writing questions, worth 90 marks and 31% of the total. Paper 2 covers topics 6-10 and follows the same format, also worth 90 marks and 31%. Paper 3 is a synoptic paper that tests content from all topics and includes a pre-released scientific article, worth 120 marks and 38% of the total. There is no coursework; however, students must complete a minimum of twelve core practicals to achieve the Practical Endorsement, which is reported separately.

    Why Choose Pearson Edexcel?

    • Edexcel Biology B offers a clear, logical structure that helps students see the bigger picture of biology, making it easier to connect ideas across different topics.
    • The course includes a synoptic paper with a pre-released article, which develops critical reading and analysis skills highly valued by universities.
    • Edexcel provides a wide range of support materials, including past papers, mark schemes, and exemplar answers, giving students ample opportunity to practice and refine exam technique.

    Frequently Asked Questions

    What is the difference between Edexcel Biology A and Biology B?
    Biology A (Salters-Nuffield) is a context-led course that starts with real-world scenarios and then explores the underlying biology. Biology B is a concept-led course that begins with fundamental biological principles and then applies them to different contexts. Both are equally respected by universities, but Biology B may suit students who prefer a more traditional, systematic approach to learning.
    How many exams are there in Edexcel A-Level Biology B and what do they cover?
    There are three exams: Paper 1 covers topics 1-5, Paper 2 covers topics 6-10, and Paper 3 is a synoptic paper covering all topics plus a pre-released scientific article. Each paper includes a mix of question types, and Paper 3 also assesses practical skills. All exams are sat at the end of the second year.
    Is there a practical endorsement for Edexcel A-Level Biology B?
    Yes, students must complete a minimum of twelve core practical activities throughout the course to achieve the Practical Endorsement. This is assessed by your teacher and is reported separately from your A-Level grade. It demonstrates your competence in practical skills and is required for some university courses.
    What topics are covered in Edexcel A-Level Biology B?
    The course covers ten topics, including biological molecules, cells, exchange and transport, genetics, energy transfers, homeostasis, evolution, and gene expression. There are also two optional topics: Microbiology and Pathogens, and Modern Genetics. The topics are designed to build a comprehensive understanding of biology from molecules to ecosystems.
    How can I prepare effectively for the Edexcel Biology B exams?
    Start by thoroughly learning the specification content and using the Edexcel past papers to practice exam technique. Focus on understanding key concepts rather than rote memorisation, and make sure you can apply your knowledge to unfamiliar contexts. For Paper 3, practice analysing scientific articles and interpreting data. Regular revision and active recall will help you succeed.
    Assessment and exam guidance

    Assessment Objectives

    AO1
    31%-33%

    Demonstrate knowledge and understanding of scientific ideas, processes, techniques and procedures.

    AO2
    41%-43%

    Apply knowledge and understanding of scientific ideas, processes, techniques and procedures in a theoretical context, in a practical context, when handling qualitative data and when handling quantitative data.

    AO3
    25%-27%

    Analyse, interpret and evaluate scientific information, ideas and evidence, including in relation to issues, to make judgements and reach conclusions and to develop and refine practical design and procedures.

    Exam Structure

    Pearson Edexcel A-Level (9BI0)

    Paper 1: Advanced Biochemistry, Microbiology and Genetics

    1h 45m

    Duration

    90

    Marks

    30%

    Weighting

    Paper 2: Advanced Physiology, Evolution and Ecology

    1h 45m

    Duration

    90

    Marks

    30%

    Weighting

    Paper 3: General and Practical Principles in Biology

    2h 30m

    Duration

    120

    Marks

    40%

    Weighting

    Tips and common mistakes

    Common Exam Mistakes

    Pitfalls to avoid in your exams

    • •Thinking all polysaccharides are identical: correction is that starch is amylose plus amylopectin, glycogen is highly branched, and cellulose has straight chains with beta glucose.
    • •Saying condensation adds water: correction is that condensation releases water, while hydrolysis uses water to split a glycosidic bond.
    • •Confusing alpha and beta glucose: correction is that they differ only in the hydroxyl group position on carbon 1.
    • •Mixing up the disaccharide components: correction is sucrose from glucose and fructose, lactose from glucose and galactose, maltose from two glucose units.
    • •Saying a triglyceride contains three ester bonds but forgetting water is released: correction is that each condensation releases one water molecule as an ester bond forms.
    • •Treating saturated and unsaturated as about energy content only: correction is that the key difference is the presence or absence of carbon-carbon double bonds in the fatty acid chains.
    • •Describing phospholipids as having three fatty acids: correction is that phospholipids have two fatty acids plus a phosphate group.
    • •Saying the phospholipid bilayer blocks all substances: correction is that it is a barrier to water-soluble substances while allowing lipid-soluble substances through.

    Top Examiner Tips

    Expert advice for exam success

    • •Learn each disaccharide as a pair of named monosaccharides so you can answer quickly and accurately.
    • •When asked about structure and function, name the structural feature first, then state the functional advantage it gives.
    • •Use the words condensation, hydrolysis and glycosidic bond precisely in multiple-choice options.
    • •Sketch alpha and beta glucose side by side and label carbon 1 so the difference is clear.
    • •Count the bonds and water molecules: three fatty acids mean three ester bonds and three water molecules released.
    • •Use the terms hydrophilic and hydrophobic when explaining bilayer formation.
    • •Link each lipid property to a named role, such as energy storage, waterproofing, insulation or membrane function.
    • •Check whether a question asks about triglycerides or phospholipids before choosing an answer.

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