AQA · A-Level · Biology

    Course version: 7402 · Version from Sept 2016

    Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are important…

    Full specification wording

    Structure of DNA and RNA: Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are important information-carrying molecules.

    DNA and RNA are nucleic acids, polymers of nucleotides, and the information they carry lies in the sequence of bases along the strand.

    Checked against the AQA 7402 specification (opens in a new tab) on .

    • Point 1 of 7
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    DNA and RNA are nucleic acids, polymers of nucleotides, and the information they carry lies in the sequence of bases along the strand. In DNA a sequence of three bases, a triplet, codes for one amino acid, so the base sequence of a gene determines the sequence of amino acids in a polypeptide, which determines its tertiary structure and therefore its function. Because the genetic code is universal, the same triplets code for the same amino acids in almost all organisms, which is why a human gene inserted into a bacterium still yields a human protein. DNA is the long-term store: it is stable, the bases are protected on the inside of the double helix by the sugar-phosphate backbone, and it can be copied exactly.

    What earns the marks

    • The information being carried in the sequence of bases.
    • A triplet of three bases coding for one amino acid.
    • The base sequence determining the amino acid sequence, and so the primary structure, of a polypeptide.
    • DNA storing the information while RNA carries a copy of it to the ribosome.
    • The genetic code being universal, so the same triplets code for the same amino acids in different species.

    Common mistakes and how to put them right

    • Describing DNA as a protein, or saying it is built from amino acids.

    • Writing that 'DNA is universal' when the point being credited is that the genetic code is universal.

    • Saying a gene codes for a characteristic rather than for a polypeptide.

    • Confusing the triplet in DNA with the codon in mRNA and the anticodon in tRNA.

    • Claiming RNA stores genetic information in all organisms, ignoring that in cells it is DNA that does so.

    Exam tips

    • Whenever you write 'information', say what form it takes: a sequence of bases.
    • One gene, one polypeptide. Keep that phrase, because 'codes for a protein' loses marks where a protein has several polypeptides.
    • In recombinant DNA questions, the mark is for the universal genetic code, so write that phrase in full.

    Try the lesson

    The start of the Structure of DNA and RNA: Deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) are important information-carrying molecules. lesson, made from checked teaching notes for this specification point.

    Have a go first

    DNA and RNA are both important information-carrying molecules. Which statement correctly describes how these molecules carry genetic information?

    Listen

    DNA and RNA are nucleic acids, polymers of nucleotides, and the information they carry lies in the sequence of bases along the strand. In DNA a sequence of three bases, a triplet, codes for one amino acid, so the base sequence of a gene determines the sequence of amino acids in a polypeptide, which determines its tertiary structure and therefore its function. Because the genetic code is universal, the same triplets code for the same amino acids in almost all organisms, which is why a human gene inserted into a bacterium still yields a human protein. DNA is the long-term store: it is stable, the bases are protected on the inside of the double helix by the sugar-phosphate backbone, and it can be copied exactly. A strong answer earns marks for these points. the information being carried in the sequence of bases. a triplet of three bases coding for one amino acid. the base sequence determining the amino acid sequence, and so the primary structure, of a polypeptide. DNA storing the information while RNA carries a copy of it to the ribosome. Exam tip: Whenever you write 'information', say what form it takes: a sequence of bases.

    Key words

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    nucleic acids

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    base sequence

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    triplet code

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    universal genetic code

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    See every definition
    nucleic acids
    DNA and RNA are important information-carrying molecules, and both are polymers of nucleotides.
    base sequence
    The information carried lies in the sequence of bases along the strand.
    triplet code
    In DNA a sequence of three bases codes for one amino acid.
    universal genetic code
    The same triplets code for the same amino acids in almost all organisms, so a human gene inserted into a bacterium still yields a human protein.

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