AQA · A-Level · Biology

    Course version: 7402 · Version from Sept 2016

    The basic structure of all cell membranes, including cell-surface…

    Full specification wording

    Transport across cell membranes: The basic structure of all cell membranes, including cell-surface membranes and the membranes around the cell organelles of eukaryotes, is the same.

    Every membrane in a cell is built to the same basic plan: a phospholipid bilayer about 7 nanometres thick with proteins embedded in it.

    Checked against the AQA 7402 specification (opens in a new tab) on .

    • Point 1 of 8
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Every membrane in a cell is built to the same basic plan: a phospholipid bilayer about 7 nanometres thick with proteins embedded in it. The reason lies in the phospholipid molecule itself, which has a hydrophilic phosphate head and two hydrophobic fatty acid tails. In an aqueous environment the molecules arrange themselves automatically so that the heads face the water on each side of the membrane while the tails point inwards away from it, producing a stable double layer. Because that arrangement follows from the molecule, it is the same whether you are looking at the cell-surface membrane, the double membrane of the nuclear envelope, mitochondrion or chloroplast, the endoplasmic reticulum, the Golgi apparatus, a lysosome or a vesicle. Membranes differ in the proteins and lipids they contain, which gives each membrane its particular functions.

    What earns the marks

    • Every membrane consisting of a phospholipid bilayer with proteins embedded in it.
    • Explaining the bilayer from hydrophilic phosphate heads facing the aqueous surroundings and hydrophobic fatty acid tails facing inwards.
    • Naming organelle membranes built on the same plan, such as the nuclear envelope, mitochondrial or chloroplast membranes, endoplasmic reticulum, Golgi apparatus, lysosomes and vesicles.
    • The difference between membranes lying in the proteins and lipids present rather than in the basic bilayer structure.
    • The shared structure allowing membranes to fuse, for example when vesicles join the cell-surface membrane.

    Common mistakes and how to put them right

    • Describing organelle membranes as structurally different from the cell-surface membrane.

    • Putting the fatty acid tails on the outside facing the aqueous surroundings and the heads inwards.

    • Writing phospholipid layer rather than phospholipid bilayer.

    • Calling the membrane a cell wall, or claiming an animal cell has both.

    • Saying membranes differ only in their proteins, when lipid composition (cholesterol, glycolipids, phospholipid types) also differs.

    Exam tips

    • Explain the bilayer from the properties of the phospholipid; simply stating that there are two layers is a description, not an explanation.
    • Name a specific organelle membrane when asked for an example; organelles is too vague.
    • Remember the number: about 7 nanometres, which is why membranes cannot be resolved with a light microscope.

    Try the lesson

    The start of the Transport across cell membranes: The basic structure of all cell membranes, including cell-surface membranes and the membranes around the cell organelles of eukaryotes, is the same. lesson, made from checked teaching notes for this specification point.

    Have a go first

    Which two classes of molecule form the main structural framework of all cell membranes?

    Listen

    Every membrane in a cell is built to the same basic plan: a phospholipid bilayer about 7 nanometres thick with proteins embedded in it. The reason lies in the phospholipid molecule itself, which has a hydrophilic phosphate head and two hydrophobic fatty acid tails. In an aqueous environment the molecules arrange themselves automatically so that the heads face the water on each side of the membrane while the tails point inwards away from it, producing a stable double layer. Because that arrangement follows from the molecule, it is the same whether you are looking at the cell-surface membrane, the double membrane of the nuclear envelope, mitochondrion or chloroplast, the endoplasmic reticulum, the Golgi apparatus, a lysosome or a vesicle. Membranes differ in the proteins and lipids they contain, which gives each membrane its particular functions. A strong answer earns marks for these points. every membrane consisting of a phospholipid bilayer with proteins embedded in it. explaining the bilayer from hydrophilic phosphate heads facing the aqueous surroundings and hydrophobic fatty acid tails facing inwards. naming organelle membranes built on the same plan, such as the nuclear envelope, mitochondrial or chloroplast membranes, endoplasmic reticulum, Golgi apparatus, lysosomes and vesicles. the difference between membranes lying in the proteins and lipids present rather than in the basic bilayer structure. Exam tip: Explain the bilayer from the properties of the phospholipid; simply stating that there are two layers is a description, not an explanation.

    See it

    A top-down flowchart. A phospholipid molecule splits into two parts: a hydrophilic phosphate head and two hydrophobic fatty acid tails. The heads face the water on each side, and the tails point inwards away from water. Both of these lead to a stable phospholipid bilayer. Proteins are embedded in the bilayer. This gives the same basic structure in all membranes, and membranes differ in the proteins and lipids they contain.
    It shows how the two ends of a phospholipid molecule lead to a stable bilayer with embedded proteins, the basic structure shared by all membranes.

    Key words

    Say what each word means before you turn the card.

    phospholipid bilayer

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    hydrophilic heads and hydrophobic tails

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    organelle membranes

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    proteins and lipids give specialisation

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    See every definition
    phospholipid bilayer
    A stable double layer about 7 nanometres thick with proteins embedded in it, formed because the molecules arrange themselves automatically in an aqueous environment.
    hydrophilic heads and hydrophobic tails
    The phosphate head faces the water on each side of the membrane while the two fatty acid tails point inwards away from it.
    organelle membranes
    The nuclear envelope, mitochondrion, chloroplast, endoplasmic reticulum, Golgi apparatus, lysosome or vesicle are built on the same basic plan as the cell-surface membrane.
    proteins and lipids give specialisation
    Membranes differ in the proteins and lipids they contain, which gives each membrane its particular functions.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A top-down flowchart. A phospholipid molecule splits into two parts: a hydrophilic phosphate head and two hydrophobic fatty acid tails. The heads face the water on each side, and the tails point inwards away from water. Both of these lead to a stable phospholipid bilayer. Proteins are embedded in the bilayer. This gives the same basic structure in all membranes, and membranes differ in the proteins and lipids they contain.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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