AQA · GCSE · Combined Science

    Course version: 8464 · Version from Sept 2018

    Homeostasis: In the human body, these include control of:

    Homeostasis keeps the internal environment of the body steady despite changes inside and outside it.

    Checked against the AQA 8464 specification (opens in a new tab) on .

    • Point 3 of 11
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Homeostasis keeps the internal environment of the body steady despite changes inside and outside it. In the human body, the automatic control systems that achieve this include control of blood glucose concentration, body temperature and water and ion balance. Each controlled factor has a normal set point, receptors that detect deviation, a coordination centre such as the brain or pancreas, and effectors such as muscles or glands that restore the set point. For example, if core temperature rises during exercise, sweating and vasodilation increase heat loss; if it falls, shivering and vasoconstriction conserve heat. Negative feedback reverses the original change, so the factor oscillates narrowly around its set point rather than drifting. This statement introduces the list of controlled factors that later statements develop in detail.

    What earns the marks

    • Homeostasis maintains a stable internal environment despite external and internal changes.
    • Human control systems include blood glucose concentration, body temperature, and water and ion balance.
    • Each system uses receptors, a coordination centre and effectors in a negative feedback loop.
    • Negative feedback reverses a detected change to return a factor towards its set point.
    • Effectors are muscles or glands that bring about the corrective response.
    • Control is automatic and antagonistic, for example insulin and glucagon or sweating and shivering.

    Common mistakes and how to put them right

    • Thinking homeostasis keeps conditions perfectly constant.

      Put it right: It actually keeps them within a narrow range around a set point, so values fluctuate slightly.

    • Confusing the coordination centre with the effector.

      Put it right: The coordination centre processes information, whereas the effector carries out the response.

    • Describing positive feedback as the usual mechanism.

      Put it right: Human homeostasis normally uses negative feedback, which reverses the change.

    Exam tips

    • Name at least two specific factors controlled in the human body, such as blood glucose concentration and body temperature, rather than saying 'everything'.
    • Use the sequence receptor → coordination centre → effector → response when explaining any control system.
    • Link each example to negative feedback by stating what the response does to the original change.

    Try the lesson

    The start of the Homeostasis: In the human body, these include control of: lesson, made from checked teaching notes for this specification point.

    Have a go first

    Which of the following are examples of conditions controlled by homeostasis in the human body?

    Listen

    Homeostasis keeps the internal environment of the body steady despite changes inside and outside it. In the human body, the automatic control systems that achieve this include control of blood glucose concentration, body temperature and water and ion balance. Each controlled factor has a normal set point, receptors that detect deviation, a coordination centre such as the brain or pancreas, and effectors such as muscles or glands that restore the set point. For example, if core temperature rises during exercise, sweating and vasodilation increase heat loss; if it falls, shivering and vasoconstriction conserve heat. Negative feedback reverses the original change, so the factor oscillates narrowly around its set point rather than drifting. This statement introduces the list of controlled factors that later statements develop in detail. A strong answer earns marks for these points. Homeostasis maintains a stable internal environment despite external and internal changes. Human control systems include blood glucose concentration, body temperature, and water and ion balance. Each system uses receptors, a coordination centre and effectors in a negative feedback loop. Negative feedback reverses a detected change to return a factor towards its set point. Exam tip: Name at least two specific factors controlled in the human body, such as blood glucose concentration and body temperature, rather than saying 'everything'.

    See it

    A flowchart running from top to bottom. The first box reads 'Change in a controlled factor' and points to 'Receptors detect deviation'. This points to 'Coordination centre (e.g. brain or pancreas)', which points to 'Effectors (muscles or glands)'. That points to 'Corrective response', which points to 'Negative feedback reverses the original change'. The final box reads 'Factor returns towards its set point'.
    It shows the negative feedback pathway from a detected change through receptors, coordination centre and effectors to a response that returns the factor towards its set point.

    Put it in order

    Put these steps in the order they happen.

    1. 1. Factor returns towards its set point
    2. 2. Negative feedback reverses the original change
    3. 3. Coordination centre (e.g. brain or pancreas)
    4. 4. Corrective response
    5. 5. Change in a controlled factor
    6. 6. Receptors detect deviation
    7. 7. Effectors (muscles or glands)

    Key words

    Say what each word means before you turn the card.

    Homeostasis

    Try answering aloud or in your head before turning the card.

    Negative feedback

    Try answering aloud or in your head before turning the card.

    Receptors, coordination centres and effectors

    Try answering aloud or in your head before turning the card.

    Antagonistic effectors and set points

    Try answering aloud or in your head before turning the card.

    See every definition
    Homeostasis
    Keeps the internal environment of the body steady despite changes inside and outside it.
    Negative feedback
    Reverses the original change, so the factor oscillates narrowly around its set point rather than drifting.
    Receptors, coordination centres and effectors
    Each controlled factor has receptors that detect deviation, a coordination centre such as the brain or pancreas, and effectors such as muscles or glands that restore the set point.
    Antagonistic effectors and set points
    Each controlled factor has a normal set point, and control is automatic and antagonistic, for example insulin and glucagon or sweating and shivering.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A flowchart running from top to bottom. The first box reads 'Change in a controlled factor' and points to 'Receptors detect deviation'. This points to 'Coordination centre (e.g. brain or pancreas)', which points to 'Effectors (muscles or glands)'. That points to 'Corrective response', which points to 'Negative feedback reverses the original change'. The final box reads 'Factor returns towards its set point'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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