AQA · GCSE · Combined Science

    Course version: 8464 · Version from Sept 2018

    Students should be able to explain that homeostasis is the regulation of…

    Full specification wording

    Homeostasis: Students should be able to explain that homeostasis is the regulation of the internal conditions of a cell or organism to maintain optimum conditions for function in response to internal and external changes.

    Homeostasis keeps the internal conditions of a cell or organism within narrow limits so that functions such as enzyme activity continue at an optimum rate.

    Checked against the AQA 8464 specification (opens in a new tab) on .

    • Point 1 of 11
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Homeostasis keeps the internal conditions of a cell or organism within narrow limits so that functions such as enzyme activity continue at an optimum rate. Internal changes include temperature, blood glucose concentration and water content; external changes include air temperature, exercise and diet. Receptors detect a change (stimulus), a coordination centre processes the information, and effectors (muscles or glands) bring about a response that reverses the change. For example, when body temperature rises during exercise, thermoreceptors detect it, the brain coordinates a response, and sweat glands and skin blood vessels cool the body. This negative feedback restores optimum conditions.

    What earns the marks

    • Homeostasis is the regulation of internal conditions within narrow limits, not a fixed unchanging state.
    • Receptors detect stimuli, coordination centres process information, and effectors produce responses.
    • Negative feedback reverses the detected change to restore optimum conditions.

    Common mistakes and how to put them right

    • Saying homeostasis keeps conditions completely constant.

      Put it right: It keeps conditions within narrow limits around an optimum, so small fluctuations occur.

    • Confusing effectors with receptors.

      Put it right: Receptors detect the stimulus, while effectors such as muscles or glands carry out the response.

    • Describing positive feedback as the main mechanism.

      Put it right: Most homeostatic control uses negative feedback, which reverses the change.

    Exam tips

    • Use the sequence stimulus → receptor → coordination centre → effector → response when explaining a homeostatic example.
    • Name one internal change and one external change, then state the response that reverses each.
    • Link the explanation to optimum conditions for enzyme action rather than saying only that the body stays the same.

    Try the lesson

    The start of the Homeostasis: Students should be able to explain that homeostasis is the regulation of the internal conditions of a cell or organism to maintain optimum conditions for function in response to internal and external changes. lesson, made from checked teaching notes for this specification point.

    Have a go first

    What name is given to the regulation of the internal conditions of an organism to maintain optimum conditions for function?

    Listen

    Homeostasis keeps the internal conditions of a cell or organism within narrow limits so that functions such as enzyme activity continue at an optimum rate. Internal changes include temperature, blood glucose concentration and water content; external changes include air temperature, exercise and diet. Receptors detect a change (stimulus), a coordination centre processes the information, and effectors (muscles or glands) bring about a response that reverses the change. For example, when body temperature rises during exercise, thermoreceptors detect it, the brain coordinates a response, and sweat glands and skin blood vessels cool the body. This negative feedback restores optimum conditions. A strong answer earns marks for these points. Homeostasis is the regulation of internal conditions within narrow limits, not a fixed unchanging state. Receptors detect stimuli, coordination centres process information, and effectors produce responses. Negative feedback reverses the detected change to restore optimum conditions. A common slip: Saying homeostasis keeps conditions completely constant. Instead, it keeps conditions within narrow limits around an optimum, so small fluctuations occur. Exam tip: Use the sequence stimulus → receptor → coordination centre → effector → response when explaining a homeostatic example.

    Key words

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    Negative feedback

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    Receptors, coordination centres and effectors

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    Response to internal and external change

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    Regulation of internal conditions

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    See every definition
    Negative feedback
    A response that reverses the detected change to restore optimum conditions.
    Receptors, coordination centres and effectors
    Receptors detect stimuli, coordination centres process information, and effectors produce responses.
    Response to internal and external change
    Operating in response to internal changes, such as blood glucose concentration, and external changes, such as air temperature.
    Regulation of internal conditions
    Keeping the internal conditions of a cell or organism within narrow limits to maintain optimum conditions for function.

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