AQA · GCSE · Combined Science

    Course version: 8464 · Version from Sept 2018

    Human endocrine system: pituitary gland

    The pituitary gland is a small endocrine gland located at the base of the brain.

    Checked against the AQA 8464 specification (opens in a new tab) on .

    • Point 5 of 10
    • 2 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    The pituitary gland is a small endocrine gland located at the base of the brain. It is often called the master gland because it secretes several hormones into the blood in response to body conditions. These hormones in turn act on other endocrine glands, stimulating them to release different hormones that bring about specific effects. For example, the pituitary secretes thyroid-stimulating hormone (TSH), which travels in the blood to the thyroid gland and stimulates it to release thyroxine. Similarly, it releases FSH to stimulate the ovaries. In exams, students may be asked to name the pituitary gland, identify its position, or explain why it is referred to as the master gland using a valid example.

    What earns the marks

    • Names the pituitary gland as a gland located in the brain that secretes hormones directly into the bloodstream.
    • States that pituitary hormones travel in the blood plasma to specific target organs.
    • Explains that the pituitary is called the master gland because its hormones control the activity of other endocrine glands.
    • Uses a named example, such as TSH stimulating the thyroid gland to release thyroxine, or FSH acting on the ovaries.
    • Describes the difference between nervous and hormonal coordination, noting that hormonal responses are carried by blood and are generally slower but longer lasting.

    Common mistakes and how to put them right

    • Thinking the pituitary gland is in the abdomen.

      Put it right by locating it at the base of the brain.

    • Saying pituitary hormones travel along nerves.

      Put it right by stating that hormones are secreted into the blood and carried to target organs.

    • Confusing the pituitary with the pancreas or thyroid.

      Put it right by linking the pituitary to the control of other glands, rather than direct control of blood glucose or metabolic rate.

    Exam tips

    • Use the phrase master gland only with a reason, specifically that its hormones stimulate other endocrine glands to release their own hormones.
    • When describing pituitary action, clearly distinguish between the hormone released by the pituitary (e.g. TSH) and the hormone released by the target gland (e.g. thyroxine).

    Try the lesson

    The start of the Human endocrine system: pituitary gland lesson, made from checked teaching notes for this specification point.

    Have a go first

    Which gland in the human endocrine system is often called the master gland?

    Listen

    The pituitary gland is a small endocrine gland located at the base of the brain. It is often called the master gland because it secretes several hormones into the blood in response to body conditions. These hormones in turn act on other endocrine glands, stimulating them to release different hormones that bring about specific effects. For example, the pituitary secretes thyroid-stimulating hormone (TSH), which travels in the blood to the thyroid gland and stimulates it to release thyroxine. Similarly, it releases FSH to stimulate the ovaries. In exams, students may be asked to name the pituitary gland, identify its position, or explain why it is referred to as the master gland using a valid example. A strong answer earns marks for these points. Names the pituitary gland as a gland located in the brain that secretes hormones directly into the bloodstream. States that pituitary hormones travel in the blood plasma to specific target organs. Explains that the pituitary is called the master gland because its hormones control the activity of other endocrine glands. Uses a named example, such as TSH stimulating the thyroid gland to release thyroxine, or FSH acting on the ovaries. A common slip: Thinking the pituitary gland is in the abdomen. Instead, locating it at the base of the brain. Exam tip: Use the phrase master gland only with a reason, specifically that its hormones stimulate other endocrine glands to release their own hormones.

    See it

    A flowchart running from top to bottom. The first box reads 'Pituitary gland at the base of the brain' and points to a second box, 'Secretes hormones into the blood'. This points to a third box, 'Hormones travel in the blood plasma to target organs'. From this third box two branches lead out: one to 'TSH stimulates the thyroid gland', which leads on to 'Thyroid gland releases thyroxine'; the other to 'FSH stimulates the ovaries'. Separately, the first box also points to a final box reading 'Called the master gland because its hormones control other endocrine glands'.
    It shows the pituitary gland secreting hormones into the blood, which travel to target organs such as the thyroid gland and ovaries, and why it is called the master gland.

    Key words

    Say what each word means before you turn the card.

    Master gland

    Try answering aloud or in your head before turning the card.

    Hormones in the bloodstream

    Try answering aloud or in your head before turning the card.

    See every definition
    Master gland
    A name for the pituitary because its hormones act on other endocrine glands, stimulating them to release different hormones that bring about specific effects.
    Hormones in the bloodstream
    Hormones secreted into the blood in response to body conditions, travelling in the blood to target organs such as the thyroid gland or the ovaries.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A flowchart running from top to bottom. The first box reads 'Pituitary gland at the base of the brain' and points to a second box, 'Secretes hormones into the blood'. This points to a third box, 'Hormones travel in the blood plasma to target organs'. From this third box two branches lead out: one to 'TSH stimulates the thyroid gland', which leads on to 'Thyroid gland releases thyroxine'; the other to 'FSH stimulates the ovaries'. Separately, the first box also points to a final box reading 'Called the master gland because its hormones control other endocrine glands'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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