AQA · A-Level · Physical Education

    Course version: 7582 · Version from Sept 2016

    Respiratory system: Carbon dioxide.

    Carbon dioxide is a primary byproduct of aerobic respiration and acts as the main chemical stimulus for the control of ventilation.

    Checked against the AQA 7582 specification (opens in a new tab) on .

    • Point 12 of 17
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Carbon dioxide is a primary byproduct of aerobic respiration and acts as the main chemical stimulus for the control of ventilation. During exercise, working muscles produce more carbon dioxide, which dissolves in the blood plasma and lowers blood pH, increasing acidity. This change is detected by chemoreceptors located in the carotid arteries, aortic arch, and medulla oblongata. The chemoreceptors send nerve impulses to the respiratory control centre (RCC) in the brain. The RCC then sends somatic motor impulses via the phrenic nerve to the diaphragm and intercostal nerves to the intercostal muscles. This increases the rate and depth of breathing to expel the excess carbon dioxide and restore blood pH to normal resting levels.

    What earns the marks

    • Carbon dioxide is the main chemical stimulus for regulating pulmonary ventilation.
    • Increased carbon dioxide levels during exercise lower blood pH, increasing blood acidity.
    • Chemoreceptors detect this increase in carbon dioxide and decrease in pH.
    • Chemoreceptors send impulses to the respiratory control centre, which sends somatic impulses via the phrenic and intercostal nerves to increase breathing rate and depth.

    Common mistakes and how to put them right

    • Believing oxygen is the primary stimulus to breathe.

      Put it right: Carbon dioxide levels and the resulting pH changes are the main chemical drivers for ventilation.

    • Stating that the autonomic nervous system directly innervates the diaphragm.

      Put it right: The RCC sends somatic motor impulses via the phrenic and intercostal nerves.

    • Forgetting to mention blood pH.

      Put it right: An increase in carbon dioxide directly lowers blood pH, which is what the chemoreceptors detect.

    Exam tips

    • Always link an increase in carbon dioxide to a decrease in blood pH when discussing chemical control of breathing.
    • Name chemoreceptors as the specific sensory receptors that detect changes in carbon dioxide.
    • Explain the full sequence: increased carbon dioxide lowers pH, stimulating chemoreceptors, which activate the RCC to send somatic impulses to respiratory muscles.

    Try the lesson

    The start of the Respiratory system: Carbon dioxide. lesson, made from checked teaching notes for this specification point.

    Have a go first

    During steady aerobic exercise, which waste gas is produced by working skeletal muscle and carried away in the blood?

    Listen

    Carbon dioxide is a primary byproduct of aerobic respiration and acts as the main chemical stimulus for the control of ventilation. During exercise, working muscles produce more carbon dioxide, which dissolves in the blood plasma and lowers blood pH, increasing acidity. This change is detected by chemoreceptors located in the carotid arteries, aortic arch, and medulla oblongata. The chemoreceptors send nerve impulses to the respiratory control centre (RCC) in the brain. The RCC then sends somatic motor impulses via the phrenic nerve to the diaphragm and intercostal nerves to the intercostal muscles. This increases the rate and depth of breathing to expel the excess carbon dioxide and restore blood pH to normal resting levels. A strong answer earns marks for these points. Carbon dioxide is the main chemical stimulus for regulating pulmonary ventilation. Increased carbon dioxide levels during exercise lower blood pH, increasing blood acidity. Chemoreceptors detect this increase in carbon dioxide and decrease in pH. Chemoreceptors send impulses to the respiratory control centre, which sends somatic impulses via the phrenic and intercostal nerves to increase breathing rate and depth. Exam tip: Always link an increase in carbon dioxide to a decrease in blood pH when discussing chemical control of breathing.

    See it

    A top-to-bottom flowchart with nine boxes connected by arrows. The first box reads 'Increased carbon dioxide from working muscles' and points to 'Carbon dioxide dissolves in blood plasma', which points to 'Blood pH lowered, acidity increased'. That points to 'Chemoreceptors detect change', then to 'Impulses sent to respiratory control centre', then to 'Somatic motor impulses via phrenic and intercostal nerves', then to 'Diaphragm and intercostal muscles', then to 'Increased rate and depth of breathing', and finally to 'Excess carbon dioxide expelled, blood pH restored'.
    It shows the sequence by which increased carbon dioxide lowers blood pH, is detected by chemoreceptors, and triggers the respiratory control centre to increase breathing.

    Key words

    Say what each word means before you turn the card.

    Carbon dioxide as a chemical stimulus

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    Blood pH and acidity

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    Chemoreceptors and sensory detection

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    Regulation of ventilation during exercise

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    See every definition
    Carbon dioxide as a chemical stimulus
    A primary byproduct of aerobic respiration that acts as the main chemical stimulus for the control of ventilation.
    Blood pH and acidity
    Carbon dioxide dissolving in the blood plasma lowers blood pH, increasing acidity.
    Chemoreceptors and sensory detection
    Receptors located in the carotid arteries, aortic arch, and medulla oblongata that detect changes in carbon dioxide and pH.
    Regulation of ventilation during exercise
    The respiratory control centre sends somatic motor impulses via the phrenic and intercostal nerves to increase the rate and depth of breathing.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A top-to-bottom flowchart with nine boxes connected by arrows. The first box reads 'Increased carbon dioxide from working muscles' and points to 'Carbon dioxide dissolves in blood plasma', which points to 'Blood pH lowered, acidity increased'. That points to 'Chemoreceptors detect change', then to 'Impulses sent to respiratory control centre', then to 'Somatic motor impulses via phrenic and intercostal nerves', then to 'Diaphragm and intercostal muscles', then to 'Increased rate and depth of breathing', and finally to 'Excess carbon dioxide expelled, blood pH restored'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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