AQA · GCSE · Biology

    Course version: 8461 · Version from Sept 2018

    Each nucleotide consists of a common sugar and phosphate group with one of…

    Full specification wording

    DNA structure (biology only): Each nucleotide consists of a common sugar and phosphate group with one of four different bases attached to the sugar.

    A nucleotide is the building block of DNA.

    Checked against the AQA 8461 specification (opens in a new tab) on .

    • Point 2 of 19
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    A nucleotide is the building block of DNA. Every nucleotide has the same two parts: a sugar molecule called deoxyribose and a phosphate group. Attached to the sugar is one base, and there are four possible bases: adenine (A), cytosine (C), guanine (G) and thymine (T). Because the sugar and phosphate are common to all nucleotides, the four nucleotides differ only in which base is attached. In a DNA strand, the sugar of one nucleotide bonds to the phosphate of the next, forming a repeating sugar-phosphate backbone. The bases project from this backbone and pair with bases on the opposite strand. When describing a nucleotide, always include all three parts: sugar, phosphate and base.

    What earns the marks

    • A nucleotide contains a sugar called deoxyribose.
    • A nucleotide contains a phosphate group.
    • The sugar and phosphate are common to all nucleotides.
    • One of four different bases is attached to the sugar.
    • The four bases are adenine, cytosine, guanine and thymine.
    • Nucleotides differ from each other only in the base they contain.

    Common mistakes and how to put them right

    • Saying the base is attached to the phosphate.

      Put it right: The base is attached to the sugar.

    • Listing only two components of a nucleotide.

      Put it right: A nucleotide has a sugar, a phosphate group and a base.

    • Believing each nucleotide has a different sugar.

      Put it right: The sugar is common to all four nucleotides.

    Exam tips

    • Draw or describe a nucleotide with the base attached to the sugar, not the phosphate.
    • Name the sugar as deoxyribose to show precise knowledge.
    • Use the phrase 'common sugar and phosphate group' when contrasting the four nucleotides.

    Try the lesson

    The start of the DNA structure (biology only): Each nucleotide consists of a common sugar and phosphate group with one of four different bases attached to the sugar. lesson, made from checked teaching notes for this specification point.

    Have a go first

    In a DNA nucleotide, which part is attached to the sugar and can be one of four different types?

    Listen

    A nucleotide is the building block of DNA. Every nucleotide has the same two parts: a sugar molecule called deoxyribose and a phosphate group. Attached to the sugar is one base, and there are four possible bases: adenine (A), cytosine (C), guanine (G) and thymine (T). Because the sugar and phosphate are common to all nucleotides, the four nucleotides differ only in which base is attached. In a DNA strand, the sugar of one nucleotide bonds to the phosphate of the next, forming a repeating sugar-phosphate backbone. The bases project from this backbone and pair with bases on the opposite strand. When describing a nucleotide, always include all three parts: sugar, phosphate and base. A strong answer earns marks for these points. A nucleotide contains a sugar called deoxyribose. A nucleotide contains a phosphate group. The sugar and phosphate are common to all nucleotides. One of four different bases is attached to the sugar. A common slip: Saying the base is attached to the phosphate. Instead, the base is attached to the sugar. Exam tip: Draw or describe a nucleotide with the base attached to the sugar, not the phosphate.

    See it

    A top-down flowchart. The top node is labelled "Nucleotide" and branches into three parts: "Common sugar (deoxyribose)", "Common phosphate group", and "One base attached to the sugar". The base node then branches into four possible bases: "Adenine (A)", "Cytosine (C)", "Guanine (G)" and "Thymine (T)". This shows the sugar and phosphate are shared by all nucleotides, while the base attached to the sugar is one of four.
    Shows that a nucleotide has a common sugar and phosphate group plus one of four bases attached to the sugar.

    Key words

    Say what each word means before you turn the card.

    Nucleotide components

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    Common sugar and phosphate

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    Four bases attached to sugar

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    Sugar-phosphate backbone

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    See every definition
    Nucleotide components
    Each nucleotide consists of a common sugar and phosphate group with one of four different bases attached to the sugar.
    Common sugar and phosphate
    The sugar and phosphate are common to all nucleotides, so the four nucleotides differ only in which base is attached.
    Four bases attached to sugar
    Attached to the sugar is one base, and there are four possible bases: adenine, cytosine, guanine and thymine.
    Sugar-phosphate backbone
    In a DNA strand, the sugar of one nucleotide bonds to the phosphate of the next, forming a repeating sugar-phosphate backbone.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A top-down flowchart. The top node is labelled "Nucleotide" and branches into three parts: "Common sugar (deoxyribose)", "Common phosphate group", and "One base attached to the sugar". The base node then branches into four possible bases: "Adenine (A)", "Cytosine (C)", "Guanine (G)" and "Thymine (T)". This shows the sugar and phosphate are shared by all nucleotides, while the base attached to the sugar is one of four.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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