AQA · GCSE · Biology

    Course version: 8461 · Version from Sept 2018

    Students should be able to explain how meiosis halves the number of…

    Full specification wording

    Meiosis: Students should be able to explain how meiosis halves the number of chromosomes in gametes and fertilisation restores the full number of chromosomes.

    Meiosis is a type of cell division that produces gametes.

    Checked against the AQA 8461 specification (opens in a new tab) on .

    • Point 1 of 7

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Meiosis is a type of cell division that produces gametes. A human body cell has 46 chromosomes, arranged as 23 pairs. Meiosis halves this number, so each gamete has 23 single chromosomes. This happens because the cell divides twice: the first division separates homologous chromosomes, and the second division separates the two copies of each chromosome. The gametes are therefore haploid. At fertilisation, a male gamete and a female gamete fuse. Their nuclei join, so the chromosome numbers add together: 23 plus 23 gives 46. The resulting zygote is diploid and has the full number of chromosomes, with one set from each parent. This restoration is essential so that each new generation has the correct chromosome number and genetic information from both parents.

    What earns the marks

    • Meiosis halves the chromosome number, producing haploid gametes.
    • In humans, body cells are diploid with 46 chromosomes, while gametes are haploid with 23 chromosomes.
    • Meiosis involves two divisions, which reduces the chromosome number from diploid to haploid.
    • Fertilisation is the fusion of a male and a female gamete, and their nuclei join.
    • Fertilisation restores the diploid number because the haploid chromosome sets from the two gametes combine, for example 23 plus 23 gives 46.

    Common mistakes and how to put them right

    • Saying that meiosis produces diploid gametes.

      Put it right: Gametes are haploid.

    • Thinking that fertilisation doubles the chromosome number beyond the normal diploid number.

      Put it right: It restores the diploid number.

    • Confusing meiosis with mitosis.

      Put it right: Mitosis produces genetically identical diploid cells, while meiosis produces haploid gametes.

    Exam tips

    • Use the terms haploid and diploid correctly, and quote the human numbers 23 and 46 as a clear example.
    • Explain the two divisions of meiosis when describing how the chromosome number is halved.
    • Link fertilisation to the fusion of gamete nuclei and state that the diploid number is restored.

    Try the lesson

    The start of the Meiosis: Students should be able to explain how meiosis halves the number of chromosomes in gametes and fertilisation restores the full number of chromosomes. lesson, made from checked teaching notes for this specification point.

    Have a go first

    A human body cell contains 46 chromosomes. How many chromosomes are in a human gamete produced by meiosis?

    Listen

    Meiosis is a type of cell division that produces gametes. A human body cell has 46 chromosomes, arranged as 23 pairs. Meiosis halves this number, so each gamete has 23 single chromosomes. This happens because the cell divides twice: the first division separates homologous chromosomes, and the second division separates the two copies of each chromosome. The gametes are therefore haploid. At fertilisation, a male gamete and a female gamete fuse. Their nuclei join, so the chromosome numbers add together: 23 plus 23 gives 46. The resulting zygote is diploid and has the full number of chromosomes, with one set from each parent. This restoration is essential so that each new generation has the correct chromosome number and genetic information from both parents. A strong answer earns marks for these points. Meiosis halves the chromosome number, producing haploid gametes. In humans, body cells are diploid with 46 chromosomes, while gametes are haploid with 23 chromosomes. Meiosis involves two divisions, which reduces the chromosome number from diploid to haploid. Fertilisation is the fusion of a male and a female gamete, and their nuclei join. A common slip: Saying that meiosis produces diploid gametes. Instead, gametes are haploid. Exam tip: Use the terms haploid and diploid correctly, and quote the human numbers 23 and 46 as a clear example.

    See it

    A top-down flowchart with six boxes joined by arrows. The first box reads 'Diploid body cell: 46 chromosomes (23 pairs)'. An arrow leads to 'Meiosis: first division separates homologous chromosomes', then to 'Second division separates the two copies of each chromosome', then to 'Haploid gametes: 23 single chromosomes'. An arrow leads to 'Fertilisation: male and female gamete fuse and their nuclei join', and finally to 'Zygote: diploid, 23 plus 23 gives 46 chromosomes'.
    It shows meiosis halving the chromosome number from 46 to 23 to form haploid gametes, then fertilisation joining two gametes to restore the diploid number of 46.

    Put it in order

    Put these steps in the order they happen.

    1. 1. Second division separates the two copies of each chromosome
    2. 2. Meiosis: first division separates homologous chromosomes
    3. 3. Diploid body cell: 46 chromosomes (23 pairs)
    4. 4. Zygote: diploid, 23 plus 23 gives 46 chromosomes
    5. 5. Fertilisation: male and female gamete fuse and their nuclei join
    6. 6. Haploid gametes: 23 single chromosomes

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A top-down flowchart with six boxes joined by arrows. The first box reads 'Diploid body cell: 46 chromosomes (23 pairs)'. An arrow leads to 'Meiosis: first division separates homologous chromosomes', then to 'Second division separates the two copies of each chromosome', then to 'Haploid gametes: 23 single chromosomes'. An arrow leads to 'Fertilisation: male and female gamete fuse and their nuclei join', and finally to 'Zygote: diploid, 23 plus 23 gives 46 chromosomes'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

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