AQA · GCSE · Biology

    Course version: 8461 · Version from Sept 2018

    Viral diseases: HIV initially causes a flu-like illness.

    When a person first becomes infected with HIV, the virus multiplies in the body and the immune system responds.

    Checked against the AQA 8461 specification (opens in a new tab) on .

    • Point 4 of 9
    • 3 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    When a person first becomes infected with HIV, the virus multiplies in the body and the immune system responds. During this early stage many people develop symptoms similar to influenza, such as fever, sore throat, tiredness, headache and swollen glands. These symptoms are not caused by influenza virus; they are the body's early response to HIV. The flu-like illness may be mild and short-lived, so it can easily be mistaken for a common cold or flu. After this initial phase, the person may feel well for years while the virus continues to damage immune cells. A blood test, not the symptoms alone, is needed to confirm HIV infection.

    What earns the marks

    • States that the initial stage of HIV infection can cause symptoms resembling influenza.
    • Gives at least one example of a flu-like symptom, such as fever, sore throat, tiredness or swollen glands.
    • Recognises that these early symptoms are caused by HIV, not by influenza virus.
    • Explains that the early symptoms may be mild or short-lived and can be mistaken for another illness.
    • Notes that the person may later be asymptomatic while HIV continues to affect immune cells.
    • States that HIV infection is confirmed by a blood test rather than by symptoms alone.

    Common mistakes and how to put them right

    • Stating that HIV causes influenza.

      Put it right by saying HIV causes flu-like symptoms, but the pathogen is HIV, not influenza virus.

    • Believing that no symptoms means no infection.

      Put it right by explaining that HIV can remain without symptoms for years while damaging immune cells.

    • Confusing HIV with AIDS at the initial stage.

      Put it right by describing the early flu-like illness as the first stage of HIV infection, before AIDS develops.

    Exam tips

    • Use the phrase flu-like illness and give one named symptom to make the description precise.
    • Make clear that the symptoms are non-specific, so a blood test is needed for diagnosis.
    • Link the early stage to the later stage by noting that the person may feel well before immune damage becomes severe.

    Try the lesson

    The start of the Viral diseases: HIV initially causes a flu-like illness. lesson, made from checked teaching notes for this specification point.

    Have a go first

    What are the typical initial symptoms experienced by a person who has recently been infected with HIV?

    Listen

    When a person first becomes infected with HIV, the virus multiplies in the body and the immune system responds. During this early stage many people develop symptoms similar to influenza, such as fever, sore throat, tiredness, headache and swollen glands. These symptoms are not caused by influenza virus; they are the body's early response to HIV. The flu-like illness may be mild and short-lived, so it can easily be mistaken for a common cold or flu. After this initial phase, the person may feel well for years while the virus continues to damage immune cells. A blood test, not the symptoms alone, is needed to confirm HIV infection. A strong answer earns marks for these points. States that the initial stage of HIV infection can cause symptoms resembling influenza. Gives at least one example of a flu-like symptom, such as fever, sore throat, tiredness or swollen glands. Recognises that these early symptoms are caused by HIV, not by influenza virus. Explains that the early symptoms may be mild or short-lived and can be mistaken for another illness. A common slip: Stating that HIV causes influenza. Instead, saying HIV causes flu-like symptoms, but the pathogen is HIV, not influenza virus. Exam tip: Use the phrase flu-like illness and give one named symptom to make the description precise.

    See it

    A top-down flowchart. The top node reads "HIV infection" and points down to "Virus multiplies; immune system responds", which points down to "Flu-like illness". From "Flu-like illness" five arrows lead to separate nodes: "Symptoms: fever, sore throat, tiredness, headache, swollen glands"; "Symptoms may be mild and short-lived"; "Symptoms caused by HIV, not influenza virus"; "Blood test needed to confirm HIV"; and "Person may feel well for years while virus damages immune cells". The node "Symptoms may be mild and short-lived" points down to a further node reading "Can be mistaken for a cold or flu".
    Shows that HIV infection leads to a flu-like illness with non-specific symptoms caused by HIV rather than influenza virus, which may be mild and mistaken for another illness and requires a blood test to confirm.

    Key words

    Say what each word means before you turn the card.

    Viral infection and immune response

    Try answering aloud or in your head before turning the card.

    Stages of HIV infection

    Try answering aloud or in your head before turning the card.

    Diagnosis of infection

    Try answering aloud or in your head before turning the card.

    See every definition
    Viral infection and immune response
    When a person first becomes infected with HIV, the virus multiplies in the body and the immune system responds.
    Stages of HIV infection
    HIV initially causes a flu-like illness, after which the person may feel well for years while the virus continues to damage immune cells.
    Diagnosis of infection
    A blood test, not the symptoms alone, is needed to confirm HIV infection.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A top-down flowchart. The top node reads "HIV infection" and points down to "Virus multiplies; immune system responds", which points down to "Flu-like illness". From "Flu-like illness" five arrows lead to separate nodes: "Symptoms: fever, sore throat, tiredness, headache, swollen glands"; "Symptoms may be mild and short-lived"; "Symptoms caused by HIV, not influenza virus"; "Blood test needed to confirm HIV"; and "Person may feel well for years while virus damages immune cells". The node "Symptoms may be mild and short-lived" points down to a further node reading "Can be mistaken for a cold or flu".
    • 1Box 1

    • 2Box 2

    • 3Box 3

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