AQA · GCSE · Combined Science

    Course version: 8464 · Version from Sept 2018

    Students should be able to describe genetic engineering as a process which…

    Full specification wording

    Genetic engineering: Students should be able to describe genetic engineering as a process which involves modifying the genome of an organism by introducing a gene from another organism to give a desired characteristic.

    Genetic engineering changes an organism's genome by transferring a gene from a donor organism so the recipient gains a desired characteristic.

    Checked against the AQA 8464 specification (opens in a new tab) on .

    • Point 1 of 12
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Genetic engineering changes an organism's genome by transferring a gene from a donor organism so the recipient gains a desired characteristic. The gene is cut out using enzymes, then inserted into a vector, often a bacterial plasmid, which carries it into the recipient cell. The recipient's genome is thereby modified and, when the gene is expressed, the new protein gives the wanted feature. For example, the human insulin gene can be inserted into a bacterium, which then produces human insulin. The process therefore has three linked ideas: modifying the genome, introducing a gene from another organism, and obtaining a desired characteristic.

    What earns the marks

    • Genetic engineering alters the genetic material of an organism, so its genome is modified.
    • A gene is taken from a donor organism and introduced into a different recipient organism.
    • The transferred gene is usually carried by a vector, commonly a bacterial plasmid.
    • Enzymes are used to cut the gene from the donor DNA and to insert it into the vector.
    • The recipient cell expresses the new gene, producing a protein that gives the desired characteristic.
    • A valid example is the human insulin gene inserted into bacteria so they make human insulin.

    Common mistakes and how to put them right

    • Saying the recipient organism 'grows' a new gene rather than receiving a gene from another organism.

      Put it right by stating the gene is transferred from a donor.

    • Confusing genetic engineering with selective breeding.

      Put it right by noting that genetic engineering moves a gene between organisms, whereas selective breeding chooses parents that already carry the desired alleles.

    • Describing the gene as entering the cell on its own.

      Put it right by explaining that a vector such as a plasmid carries the gene into the recipient cell.

    Exam tips

    • Name the vector and the enzymes when describing the method, as these show the process rather than just the outcome.
    • Finish with the desired characteristic and a named example, such as disease resistance or insulin production, to show the purpose of the modification.

    Try the lesson

    The start of the Genetic engineering: Students should be able to describe genetic engineering as a process which involves modifying the genome of an organism by introducing a gene from another organism to give a desired characteristic. lesson, made from checked teaching notes for this specification point.

    Have a go first

    Which statement best describes genetic engineering?

    Listen

    Genetic engineering changes an organism's genome by transferring a gene from a donor organism so the recipient gains a desired characteristic. The gene is cut out using enzymes, then inserted into a vector, often a bacterial plasmid, which carries it into the recipient cell. The recipient's genome is thereby modified and, when the gene is expressed, the new protein gives the wanted feature. For example, the human insulin gene can be inserted into a bacterium, which then produces human insulin. The process therefore has three linked ideas: modifying the genome, introducing a gene from another organism, and obtaining a desired characteristic. A strong answer earns marks for these points. Genetic engineering alters the genetic material of an organism, so its genome is modified. A gene is taken from a donor organism and introduced into a different recipient organism. The transferred gene is usually carried by a vector, commonly a bacterial plasmid. Enzymes are used to cut the gene from the donor DNA and to insert it into the vector. A common slip: Saying the recipient organism 'grows' a new gene rather than receiving a gene from another organism. Instead, stating the gene is transferred from a donor. Exam tip: Name the vector and the enzymes when describing the method, as these show the process rather than just the outcome.

    See it

    A flowchart running from top to bottom with six steps. First, a gene is cut from donor DNA using enzymes. Second, the gene is inserted into a vector, often a bacterial plasmid. Third, the vector carries the gene into the recipient cell. Fourth, the recipient's genome is modified. Fifth, the recipient cell expresses the new gene. Sixth, the new protein gives the desired characteristic.
    It shows the sequence of steps in genetic engineering, from cutting out a gene to the recipient gaining the desired characteristic.

    Put it in order

    Put these steps in the order they happen.

    1. 1. Vector carries the gene into the recipient cell
    2. 2. Gene inserted into a vector, often a bacterial plasmid
    3. 3. Gene cut from donor DNA using enzymes
    4. 4. New protein gives the desired characteristic
    5. 5. Recipient cell expresses the new gene
    6. 6. Recipient's genome is modified

    Key words

    Say what each word means before you turn the card.

    Genetic engineering

    Try answering aloud or in your head before turning the card.

    Vector

    Try answering aloud or in your head before turning the card.

    Enzymes

    Try answering aloud or in your head before turning the card.

    Desired characteristic

    Try answering aloud or in your head before turning the card.

    See every definition
    Genetic engineering
    A process which involves modifying the genome of an organism by introducing a gene from another organism to give a desired characteristic.
    Vector
    Something that carries the gene into the recipient cell, commonly a bacterial plasmid.
    Enzymes
    Used to cut the gene from the donor DNA and to insert it into the vector.
    Desired characteristic
    The wanted feature given when the recipient cell expresses the new gene, producing a protein.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A flowchart running from top to bottom with six steps. First, a gene is cut from donor DNA using enzymes. Second, the gene is inserted into a vector, often a bacterial plasmid. Third, the vector carries the gene into the recipient cell. Fourth, the recipient's genome is modified. Fifth, the recipient cell expresses the new gene. Sixth, the new protein gives the desired characteristic.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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