AQA · GCSE · Combined Science

    Course version: 8464 · Version from Sept 2018

    Students should be able to describe the principles of hormonal…

    Full specification wording

    Human endocrine system: Students should be able to describe the principles of hormonal coordination and control by the human endocrine system.

    Hormonal coordination uses endocrine glands as effectors that release hormones directly into the blood.

    Checked against the AQA 8464 specification (opens in a new tab) on .

    • Point 1 of 10
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Hormonal coordination uses endocrine glands as effectors that release hormones directly into the blood. Each hormone travels in the blood plasma to specific target organs, where it binds to receptors and triggers a response. This produces widespread, relatively slow and long-lasting control of processes such as blood glucose concentration and growth.

    For example: The pancreas detects a rise in blood glucose and secretes insulin; insulin reaches the liver and muscle cells, causing them to take up more glucose, thereby lowering blood glucose levels.

    What earns the marks

    • Endocrine glands are effectors that secrete hormones directly into the bloodstream.
    • Hormones are chemical messengers carried in the blood plasma to target organs.
    • A target organ responds to a specific hormone because it has complementary receptors.
    • Hormonal responses are usually slower to begin than nervous responses but often last longer and affect more widespread areas.
    • Named examples include insulin from the pancreas lowering blood glucose, adrenaline from the adrenal glands, and thyroxine from the thyroid.

    Common mistakes and how to put them right

    • Writing that hormones travel along nerve cells or through ducts.

      Put it right by stating that glands secrete hormones directly into the bloodstream and the blood carries them.

    • Claiming that any cell responds to any hormone.

      Put it right by explaining that only specific target organs with complementary receptors respond.

    • Saying hormonal effects are always faster than nervous effects.

      Put it right by stating that hormonal effects are slower in onset but generally longer lasting.

    Exam tips

    • Use the terms gland, hormone, bloodstream, and target organ in every full description of the endocrine system.
    • When comparing with the nervous system, give one similarity and at least two differences, such as speed of onset and duration of effect.

    Try the lesson

    The start of the Human endocrine system: Students should be able to describe the principles of hormonal coordination and control by the human endocrine system. lesson, made from checked teaching notes for this specification point.

    Have a go first

    Which statement describes how hormones are transported in the human body?

    Listen

    Hormonal coordination uses endocrine glands as effectors that release hormones directly into the blood. Each hormone travels in the blood plasma to specific target organs, where it binds to receptors and triggers a response. This produces widespread, relatively slow and long-lasting control of processes such as blood glucose concentration and growth. For example, the pancreas detects a rise in blood glucose and secretes insulin; insulin reaches the liver and muscle cells, causing them to take up more glucose, thereby lowering blood glucose levels. A strong answer earns marks for these points. Endocrine glands are effectors that secrete hormones directly into the bloodstream. Hormones are chemical messengers carried in the blood plasma to target organs. A target organ responds to a specific hormone because it has complementary receptors. Hormonal responses are usually slower to begin than nervous responses but often last longer and affect more widespread areas. A common slip: Writing that hormones travel along nerve cells or through ducts. Instead, stating that glands secrete hormones directly into the bloodstream and the blood carries them. Exam tip: Use the terms gland, hormone, bloodstream, and target organ in every full description of the endocrine system.

    See it

    A top-to-bottom flowchart. The first box reads 'Endocrine gland (effector)' and has an arrow down to 'Hormone secreted directly into the bloodstream'. An arrow leads down to 'Hormone carried in the blood plasma', then down to 'Target organ with complementary receptors', then down to 'Response triggered'. A separate chain starts with 'Pancreas detects rise in blood glucose', arrow down to 'Insulin secreted', arrow down to 'Liver and muscle cells take up more glucose', arrow down to 'Blood glucose lowered'.
    It shows how an endocrine gland secretes a hormone into the blood, which carries it to a target organ with complementary receptors, illustrated by insulin lowering blood glucose.

    Key words

    Say what each word means before you turn the card.

    Endocrine glands

    Try answering aloud or in your head before turning the card.

    Hormones

    Try answering aloud or in your head before turning the card.

    Target organ

    Try answering aloud or in your head before turning the card.

    Hormonal responses

    Try answering aloud or in your head before turning the card.

    See every definition
    Endocrine glands
    These are effectors that secrete hormones directly into the bloodstream.
    Hormones
    Chemical messengers carried in the blood plasma to target organs.
    Target organ
    A structure that responds to a specific hormone because it has complementary receptors.
    Hormonal responses
    Usually slower to begin than nervous responses but often last longer and affect more widespread areas.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A top-to-bottom flowchart. The first box reads 'Endocrine gland (effector)' and has an arrow down to 'Hormone secreted directly into the bloodstream'. An arrow leads down to 'Hormone carried in the blood plasma', then down to 'Target organ with complementary receptors', then down to 'Response triggered'. A separate chain starts with 'Pancreas detects rise in blood glucose', arrow down to 'Insulin secreted', arrow down to 'Liver and muscle cells take up more glucose', arrow down to 'Blood glucose lowered'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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