AQA · GCSE · Combined Science

    Course version: 8464 · Version from Sept 2018

    The endocrine system is composed of glands which secrete chemicals called…

    Full specification wording

    Human endocrine system: The endocrine system is composed of glands which secrete chemicals called hormones directly into the bloodstream. The blood carries the hormone to a target organ where it produces an effect. Compared to the nervous system the effects are slower but act for longer.

    The endocrine system is a set of ductless glands that secrete hormones straight into the blood.

    Checked against the AQA 8464 specification (opens in a new tab) on .

    • Point 2 of 10
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    The endocrine system is a set of ductless glands that secrete hormones straight into the blood. Blood plasma carries each hormone throughout the body, but an effect occurs only at a target organ whose cells have receptors that bind that hormone. For example, the adrenal glands secrete adrenaline into the blood; adrenaline reaches the heart, where it increases heart rate, and the liver, where it stimulates glycogen breakdown to release glucose. Because transport is by mass flow of blood and cells must be reached and respond, hormonal effects begin more slowly than nerve impulses. However, hormones persist in the blood and are removed gradually, so their effects act for longer and can be widespread. This contrasts with the nervous system, where electrical impulses travel along neurones and produce rapid, short-lived, precisely targeted responses.

    What earns the marks

    • Endocrine glands are ductless and secrete hormones directly into the bloodstream.
    • Blood plasma transports hormones around the body to target organs.
    • A target organ has cells with receptors that the hormone binds to, producing a specific effect.
    • Hormonal effects are slower in onset than nervous effects because hormones must travel in the blood and reach target cells.
    • Hormonal effects act for longer than nervous effects because hormones persist in the blood and are broken down gradually.
    • A valid example is adrenaline from the adrenal glands increasing heart rate and blood glucose concentration.

    Common mistakes and how to put them right

    • Stating that hormones are carried by nerves.

      Put it right by saying hormones are secreted into the bloodstream and carried in the plasma.

    • Writing that hormones affect every cell equally.

      Put it right by explaining that only target organs with complementary receptors respond.

    • Confusing slower onset with weaker effect.

      Put it right by stating that hormonal effects are slower to start but often longer lasting and can be widespread.

    Exam tips

    • Use a three-part chain: gland secretes hormone, blood carries it, target organ responds.
    • For comparison questions, pair each difference with a reason, such as slower because transport is by blood rather than along neurones.
    • Name one gland, its hormone and its target organ effect to make the description concrete.

    Try the lesson

    The start of the Human endocrine system: The endocrine system is composed of glands which secrete chemicals called hormones directly into the bloodstream. The blood carries the hormone to a target organ where it produces an effect. Compared to the nervous system the effects are slower but act for longer. lesson, made from checked teaching notes for this specification point.

    Have a go first

    Which statement describes the endocrine system?

    Listen

    The endocrine system is a set of ductless glands that secrete hormones straight into the blood. Blood plasma carries each hormone throughout the body, but an effect occurs only at a target organ whose cells have receptors that bind that hormone. For example, the adrenal glands secrete adrenaline into the blood; adrenaline reaches the heart, where it increases heart rate, and the liver, where it stimulates glycogen breakdown to release glucose. Because transport is by mass flow of blood and cells must be reached and respond, hormonal effects begin more slowly than nerve impulses. However, hormones persist in the blood and are removed gradually, so their effects act for longer and can be widespread. This contrasts with the nervous system, where electrical impulses travel along neurones and produce rapid, short-lived, precisely targeted responses. A strong answer earns marks for these points. Endocrine glands are ductless and secrete hormones directly into the bloodstream. Blood plasma transports hormones around the body to target organs. A target organ has cells with receptors that the hormone binds to, producing a specific effect. Hormonal effects are slower in onset than nervous effects because hormones must travel in the blood and reach target cells. A common slip: Stating that hormones are carried by nerves. Instead, saying hormones are secreted into the bloodstream and carried in the plasma. Exam tip: Use a three-part chain: gland secretes hormone, blood carries it, target organ responds.

    See it

    A flowchart running from top to bottom. The first box reads 'Endocrine gland', which leads to 'Secretes hormone directly into the bloodstream', then to 'Blood carries the hormone', then to 'Target organ with receptors', then to 'Effect produced'. From 'Effect produced' an arrow leads to a box reading 'Effects are slower but act for longer'. A separate box reads 'Nervous system' and leads to 'Effects are faster but act for a shorter time'.
    It shows the gland-hormone-blood-target organ chain and contrasts the slower, longer-lasting hormonal effects with the faster, shorter nervous effects.

    Key words

    Say what each word means before you turn the card.

    Hormones

    Try answering aloud or in your head before turning the card.

    Target organ

    Try answering aloud or in your head before turning the card.

    Endocrine system

    Try answering aloud or in your head before turning the card.

    Nervous system

    Try answering aloud or in your head before turning the card.

    See every definition
    Hormones
    Chemicals secreted by glands directly into the bloodstream, which the blood carries to a target organ where they produce an effect.
    Target organ
    The organ where a hormone produces an effect, having cells with receptors that the hormone binds to.
    Endocrine system
    A set of ductless glands that secrete hormones straight into the blood.
    Nervous system
    A system where electrical impulses travel along neurones and produce rapid, short-lived, precisely targeted responses.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A flowchart running from top to bottom. The first box reads 'Endocrine gland', which leads to 'Secretes hormone directly into the bloodstream', then to 'Blood carries the hormone', then to 'Target organ with receptors', then to 'Effect produced'. From 'Effect produced' an arrow leads to a box reading 'Effects are slower but act for longer'. A separate box reads 'Nervous system' and leads to 'Effects are faster but act for a shorter time'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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    Test your understanding of Human endocrine system: The endocrine system is composed of glands which secrete chemicals called hormones directly into the bloodstream. The blood carries the hormone to a target organ where it produces an effect. Compared to the nervous system the effects are slower but act for longer.

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