This topic explores the definition of health and the distinction between communicable and non-communicable diseases, including the role of pathogens. It co
Topic Synopsis
This topic explores the definition of health and the distinction between communicable and non-communicable diseases, including the role of pathogens. It covers human and plant defence mechanisms, the development of medicines, and the impact of lifestyle factors on non-communicable diseases.
Key Concepts & Core Principles
- Nervous vs. hormonal control: The nervous system uses fast, electrical impulses and short-lived responses, whereas the endocrine system relies on slower, chemical hormones with longer-lasting effects.
- Negative feedback in homeostasis: Any change from the set point (e.g., rise in body temperature) triggers a response (e.g., sweating) that reverses the change, returning the system to normal. This principle applies to thermoregulation, osmoregulation, and blood glucose regulation.
- Blood glucose regulation: After a meal, insulin promotes the conversion of glucose to glycogen in the liver and muscles and increases glucose uptake by cells. When glucose levels fall, glucagon stimulates glycogen breakdown. Diabetes results from insulin deficiency (Type 1) or resistance (Type 2).
- Menstrual cycle hormone coordination: FSH stimulates follicle maturation and oestrogen release; oestrogen triggers LH surge and thickens the uterine lining; LH causes ovulation; progesterone maintains the lining and inhibits further FSH/LH production. Feedback loops control the cycle.
- Plant tropisms via auxin: Auxin is a plant hormone that promotes cell elongation. In phototropism, auxin redistributes to the shaded side of a shoot, causing cells there to elongate more, bending the shoot towards light. In gravitropism, auxin accumulates on the lower side of a root, but inhibits cell elongation in roots, causing downward growth.
Exam Tips & Revision Strategies
- Ensure you can distinguish between the lytic and lysogenic pathways of viruses
- Be prepared to calculate cross-sectional areas of bacterial cultures using pi*r^2
- Understand the ethical and practical implications of using monoclonal antibodies
- Know the specific physical and chemical barriers of the human body
- Be able to evaluate treatments for cardiovascular disease
Common Misconceptions & Mistakes to Avoid
- Confusing communicable and non-communicable diseases
- Assuming antibiotics can kill viruses
- Misunderstanding the role of memory lymphocytes in secondary immune response
- Incorrectly calculating BMI or waist:hip ratios
- Failing to describe aseptic techniques correctly in microbial culture investigations
Examiner Marking Points
- Definition of health as physical, mental and social well-being
- Distinction between communicable and non-communicable diseases
- Pathogens include viruses, bacteria, fungi and protists
- Mechanisms of pathogen spread and prevention
- Physical and chemical human body defences
- Specific immune system response (antigens, antibodies, memory lymphocytes)
- Antibiotics only treat bacterial infections
- Stages of medicine development (discovery, development, testing)