This topic explores the definition of health and the distinction between communicable and non-communicable diseases, including the role of pathogens. It co
Topic Synopsis
This topic explores the definition of health and the distinction between communicable and non-communicable diseases, including the role of pathogens. It covers human and plant defence mechanisms, the development of medicines, and the impact of lifestyle factors on non-communicable diseases.
Key Concepts & Core Principles
- The relationship between surface area to volume ratio and the need for exchange surfaces and transport systems in multicellular organisms.
- Features of efficient exchange surfaces: large surface area, thin membrane, good blood supply, and ventilation (e.g., alveoli, villi).
- The double circulatory system: pulmonary circulation (heart to lungs) and systemic circulation (heart to body), and the structure of the heart (atria, ventricles, valves, pacemaker).
- The composition and functions of blood: red blood cells (oxygen transport), white blood cells (immunity), platelets (clotting), and plasma (transport of nutrients, waste, hormones).
- Gas exchange in the alveoli: diffusion of oxygen into blood and carbon dioxide out, and the role of haemoglobin in oxygen transport.
Exam Tips & Revision Strategies
- Ensure you can distinguish between the lytic and lysogenic pathways of viruses
- Be prepared to calculate cross-sectional areas of bacterial cultures using pi*r^2
- Understand the ethical and practical implications of using monoclonal antibodies
- Know the specific physical and chemical barriers of the human body
- Be able to evaluate treatments for cardiovascular disease
Common Misconceptions & Mistakes to Avoid
- Confusing communicable and non-communicable diseases
- Assuming antibiotics can kill viruses
- Misunderstanding the role of memory lymphocytes in secondary immune response
- Incorrectly calculating BMI or waist:hip ratios
- Failing to describe aseptic techniques correctly in microbial culture investigations
Examiner Marking Points
- Definition of health as physical, mental and social well-being
- Distinction between communicable and non-communicable diseases
- Pathogens include viruses, bacteria, fungi and protists
- Mechanisms of pathogen spread and prevention
- Physical and chemical human body defences
- Specific immune system response (antigens, antibodies, memory lymphocytes)
- Antibiotics only treat bacterial infections
- Stages of medicine development (discovery, development, testing)