AQA · GCSE · Biology

    Course version: 8461 · Version from Sept 2018

    Health issues: Different types of disease may interact.

    Diseases rarely occur in isolation.

    Checked against the AQA 8461 specification (opens in a new tab) on .

    • Point 5 of 10
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Diseases rarely occur in isolation. A communicable disease can weaken the body so a non-communicable disease develops, or a non-communicable disease can make a communicable infection more likely or more severe. For example, infection with HIV destroys lymphocytes, so the immune system cannot control other pathogens and the person may develop AIDS-related infections. Conversely, a poor diet causing anaemia reduces oxygen transport, so tissues heal slowly and infection risk rises. Another interaction is that a pathogen can trigger an immune reaction that damages healthy tissue, as in rheumatic fever affecting the heart.

    What earns the marks

    • States that one disease can increase the risk of another disease developing.
    • Explains a causal mechanism, such as a weakened immune system allowing a secondary infection.
    • Uses a named example, such as HIV destroying lymphocytes so opportunistic infections occur.
    • Distinguishes between communicable and non-communicable diseases and explains how one can influence the other.
    • Describes how a pathogen can trigger an immune response that damages body tissues, leading to further disease.

    Common mistakes and how to put them right

    • Treating diseases as independent events and listing two conditions without linking them.

      Put it right by explaining the causal pathway from the first disease to the second.

    • Confusing correlation with causation, for example saying that people with a disease always catch another.

      Put it right by using words such as increases the risk or makes more likely.

    • Describing HIV as directly killing the person rather than destroying lymphocytes so the immune system fails.

      Put it right by explaining the role of lymphocytes in defence.

    Exam tips

    • Use the command word to decide whether you need a simple link or a full causal chain.
    • Name specific diseases and the cells or organs affected to make the interaction concrete.
    • Link back to the question by stating clearly how the first disease makes the second more likely.

    Try the lesson

    The start of the Health issues: Different types of disease may interact. lesson, made from checked teaching notes for this specification point.

    Have a go first

    A person has a disease that damages the lining of their airways. Which statement best describes how this disease may interact with another type of disease?

    Listen

    Diseases rarely occur in isolation. A communicable disease can weaken the body so a non-communicable disease develops, or a non-communicable disease can make a communicable infection more likely or more severe. For example, infection with HIV destroys lymphocytes, so the immune system cannot control other pathogens and the person may develop AIDS-related infections. Conversely, a poor diet causing anaemia reduces oxygen transport, so tissues heal slowly and infection risk rises. Another interaction is that a pathogen can trigger an immune reaction that damages healthy tissue, as in rheumatic fever affecting the heart. A strong answer earns marks for these points. States that one disease can increase the risk of another disease developing. Explains a causal mechanism, such as a weakened immune system allowing a secondary infection. Uses a named example, such as HIV destroying lymphocytes so opportunistic infections occur. Distinguishes between communicable and non-communicable diseases and explains how one can influence the other. A common slip: Treating diseases as independent events and listing two conditions without linking them. Instead, explaining the causal pathway from the first disease to the second. Exam tip: Use the command word to decide whether you need a simple link or a full causal chain.

    See it

    A top-to-bottom flowchart with three separate chains. The first chain starts at HIV infection, which leads to destruction of lymphocytes, which leads to the immune system being unable to control other pathogens, which leads to AIDS-related infections developing. The second chain starts at poor diet causing anaemia, which leads to reduced oxygen transport, which leads to tissues healing slowly, which leads to infection risk rising. The third chain starts at a pathogen triggering an immune reaction, which leads to the immune reaction damaging healthy tissue, which leads to further disease, for example rheumatic fever affecting the heart.
    Three causal chains showing how one disease can increase the risk of another: HIV destroying lymphocytes leading to AIDS-related infections, anaemia reducing oxygen transport leading to slower healing and higher infection risk, and a pathogen-triggered immune reaction damaging healthy tissue.

    Key words

    Say what each word means before you turn the card.

    Communicable and non-communicable disease interaction

    Try answering aloud or in your head before turning the card.

    Immune system function and failure

    Try answering aloud or in your head before turning the card.

    Causal mechanisms in disease

    Try answering aloud or in your head before turning the card.

    Risk factors and health

    Try answering aloud or in your head before turning the card.

    See every definition
    Communicable and non-communicable disease interaction
    A communicable disease can weaken the body so a non-communicable disease develops, or a non-communicable disease can make a communicable infection more likely or more severe.
    Immune system function and failure
    Infection with HIV destroys lymphocytes, so the immune system cannot control other pathogens and the person may develop AIDS-related infections.
    Causal mechanisms in disease
    A causal chain links the first disease to the second, such as a weakened immune system allowing a secondary infection.
    Risk factors and health
    A poor diet causing anaemia reduces oxygen transport, so tissues heal slowly and infection risk rises.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A top-to-bottom flowchart with three separate chains. The first chain starts at HIV infection, which leads to destruction of lymphocytes, which leads to the immune system being unable to control other pathogens, which leads to AIDS-related infections developing. The second chain starts at poor diet causing anaemia, which leads to reduced oxygen transport, which leads to tissues healing slowly, which leads to infection risk rising. The third chain starts at a pathogen triggering an immune reaction, which leads to the immune reaction damaging healthy tissue, which leads to further disease, for example rheumatic fever affecting the heart.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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