AQA · GCSE · Combined Science

    Course version: 8464 · Version from Sept 2018

    The formation of lipid molecules from a molecule of glycerol and three…

    Full specification wording

    Metabolism: the formation of lipid molecules from a molecule of glycerol and three molecules of fatty acids

    A lipid molecule is formed when one glycerol molecule joins with three fatty acid molecules in a condensation reaction.

    Checked against the AQA 8464 specification (opens in a new tab) on .

    • Point 6 of 10
    • 3 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    A lipid molecule is formed when one glycerol molecule joins with three fatty acid molecules in a condensation reaction. Glycerol has three hydroxyl groups, and each fatty acid has a carboxyl group, so three ester bonds form and three molecules of water are released. The product is a triglyceride. Fatty acids may be saturated, with only single carbon-carbon bonds, or unsaturated, with at least one carbon-carbon double bond. Lipids are stored in plants and animals as an energy store, provide insulation and protection, and are used to make cell membranes. A useful method is to count the reactants and products: one glycerol plus three fatty acids gives one triglyceride plus three water molecules.

    What earns the marks

    • One glycerol molecule reacts with three fatty acid molecules to form one lipid (triglyceride) molecule.
    • The reaction is condensation: three molecules of water are released, one for each fatty acid joined.
    • Three ester bonds form between the glycerol and the fatty acids.
    • Fatty acids may be saturated (only single carbon-carbon bonds) or unsaturated (at least one carbon-carbon double bond).
    • Lipids are an energy store in plants and animals and also provide insulation and protection.
    • Lipids are used to make cell membranes, where they form a bilayer.
    • The reaction is the reverse of hydrolysis, which uses water to break a triglyceride into glycerol and fatty acids.

    Common mistakes and how to put them right

    • Writing that one fatty acid joins glycerol.

      Put it right: , three fatty acids join one glycerol, releasing three water molecules.

    • Saying water is used up in the reaction.

      Put it right: , condensation releases water; hydrolysis uses water.

    • Confusing glycerol with glucose.

      Put it right: , glycerol is an alcohol with three hydroxyl groups, while glucose is a sugar.

    Exam tips

    • Count the reactants and products: one glycerol plus three fatty acids gives one triglyceride plus three water molecules.
    • Name the bond formed between glycerol and a fatty acid as an ester bond.
    • Link the structure of lipids to their roles, such as energy storage, insulation and cell membranes.

    Try the lesson

    The start of the Metabolism: the formation of lipid molecules from a molecule of glycerol and three molecules of fatty acids lesson, made from checked teaching notes for this specification point.

    Have a go first

    Which two types of molecule join together to form a lipid?

    Listen

    A lipid molecule is formed when one glycerol molecule joins with three fatty acid molecules in a condensation reaction. Glycerol has three hydroxyl groups, and each fatty acid has a carboxyl group, so three ester bonds form and three molecules of water are released. The product is a triglyceride. Fatty acids may be saturated, with only single carbon-carbon bonds, or unsaturated, with at least one carbon-carbon double bond. Lipids are stored in plants and animals as an energy store, provide insulation and protection, and are used to make cell membranes. A useful method is to count the reactants and products: one glycerol plus three fatty acids gives one triglyceride plus three water molecules. A strong answer earns marks for these points. One glycerol molecule reacts with three fatty acid molecules to form one lipid (triglyceride) molecule. The reaction is condensation: three molecules of water are released, one for each fatty acid joined. Three ester bonds form between the glycerol and the fatty acids. Fatty acids may be saturated (only single carbon-carbon bonds) or unsaturated (at least one carbon-carbon double bond). A common slip: Writing that one fatty acid joins glycerol. Instead, , three fatty acids join one glycerol, releasing three water molecules. Exam tip: Count the reactants and products: one glycerol plus three fatty acids gives one triglyceride plus three water molecules.

    See it

    A left-to-right flowchart. On the left are two inputs: a node labelled 'One glycerol molecule' and a node labelled 'Three fatty acid molecules'. Both arrows lead into a central node labelled 'Condensation reaction'. From this central node, three arrows lead out to three separate nodes: 'One lipid (triglyceride) molecule', 'Three molecules of water released', and 'Three ester bonds formed'.
    It shows one glycerol molecule joining with three fatty acid molecules in a condensation reaction to form one triglyceride, releasing three water molecules and forming three ester bonds.

    Key words

    Say what each word means before you turn the card.

    Triglyceride

    Try answering aloud or in your head before turning the card.

    Saturated fatty acid

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    Unsaturated fatty acid

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    See every definition
    Triglyceride
    The lipid molecule formed when one glycerol molecule reacts with three fatty acid molecules.
    Saturated fatty acid
    A fatty acid with only single carbon-carbon bonds.
    Unsaturated fatty acid
    A fatty acid with at least one carbon-carbon double bond.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A left-to-right flowchart. On the left are two inputs: a node labelled 'One glycerol molecule' and a node labelled 'Three fatty acid molecules'. Both arrows lead into a central node labelled 'Condensation reaction'. From this central node, three arrows lead out to three separate nodes: 'One lipid (triglyceride) molecule', 'Three molecules of water released', and 'Three ester bonds formed'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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