Biology A-Level
hypermethylation of tumour suppressor genes
What hypermethylation of tumour suppressor genes means in Biology A-Level, as defined for AQA.
Definition of hypermethylation of tumour suppressor genes
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Reference: AQA
The promoter region of a tumour suppressor gene becomes hypermethylated, so it is not transcribed and the protein that would slow the cell cycle or trigger apoptosis is not made.
Topics that use hypermethylation of tumour suppressor genes
Related terms
- complementary base pairing
- correlation not causation
- decreased histone acetylation
- DNA methylation
- environment and gene expression
- genotype versus environment
- histone acetylation
- increased DNA methylation
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