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    Biology A-Level

    decreased histone acetylation

    What decreased histone acetylation means in Biology A-Level, as defined for AQA.

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    Acetyl groups are removed from the histones by histone deacetylase, the histones become more positively charged, bind the negatively charged DNA more strongly, the chromatin condenses and RNA polymerase cannot reach the promoter.
    AQA · Regulation of transcription and translation (A-level only) (study guide)

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