AQA · GCSE · Biology

    Course version: 8461 · Version from Sept 2018

    Many diseases are caused by the interaction of a number of factors.

    Full specification wording

    The effect of lifestyle on some non-communicable diseases: Many diseases are caused by the interaction of a number of factors.

    Non-communicable diseases often arise from several interacting factors rather than a single cause.

    Checked against the AQA 8461 specification (opens in a new tab) on .

    • Point 6 of 9
    • 4 key terms

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Non-communicable diseases often arise from several interacting factors rather than a single cause. These factors can include genetics, lifestyle choices and environmental exposures. For example, a person may inherit a tendency towards high blood pressure, eat a diet high in saturated fat, smoke and take little exercise; together these raise the risk of cardiovascular disease more than any one factor alone. Similarly, Type 2 diabetes risk can involve obesity, diet, physical activity and family history. Because factors interact, it is difficult to prove that one factor alone causes a disease.

    What earns the marks

    • State that many non-communicable diseases have multiple contributing factors rather than one single cause.
    • Identify categories of interacting factors, such as genetic, lifestyle and environmental influences.
    • Give a named example, such as cardiovascular disease, where diet, smoking, exercise and genetics interact.
    • Explain that interacting factors can increase risk more than any single factor alone.
    • Explain why multiple factors make it difficult to prove a single causal mechanism.

    Common mistakes and how to put them right

    • Attributing a disease to one factor only.

      Put it right by describing at least two interacting factors.

    • Assuming that factors simply add up.

      Put it right by explaining that they can interact and multiply risk.

    • Ignoring genetic factors; correct this by including inherited tendencies alongside lifestyle and environment.

    Exam tips

    • Use the word 'interaction' and give a specific disease with at least two factors.
    • Structure your answer by naming the disease, then the factors, then how they combine.
    • Explain why proving one cause is difficult when several factors are involved.

    Try the lesson

    The start of the The effect of lifestyle on some non-communicable diseases: Many diseases are caused by the interaction of a number of factors. lesson, made from checked teaching notes for this specification point.

    Have a go first

    Which statement best describes why many non-communicable diseases, such as cardiovascular disease, develop?

    Listen

    Non-communicable diseases often arise from several interacting factors rather than a single cause. These factors can include genetics, lifestyle choices and environmental exposures. For example, a person may inherit a tendency towards high blood pressure, eat a diet high in saturated fat, smoke and take little exercise; together these raise the risk of cardiovascular disease more than any one factor alone. Similarly, Type 2 diabetes risk can involve obesity, diet, physical activity and family history. Because factors interact, it is difficult to prove that one factor alone causes a disease. A strong answer earns marks for these points. State that many non-communicable diseases have multiple contributing factors rather than one single cause. Identify categories of interacting factors, such as genetic, lifestyle and environmental influences. Give a named example, such as cardiovascular disease, where diet, smoking, exercise and genetics interact. Explain that interacting factors can increase risk more than any single factor alone. A common slip: Attributing a disease to one factor only. Instead, describing at least two interacting factors. Exam tip: Use the word 'interaction' and give a specific disease with at least two factors.

    See it

    A top-down flowchart. At the top, a node labelled 'Multiple interacting factors' branches into three nodes: 'Genetic factors', 'Lifestyle factors' and 'Environmental factors'. From 'Lifestyle factors' three arrows lead to 'Diet high in saturated fat', 'Smoking' and 'Little exercise'. From 'Genetic factors' one arrow leads to 'Inherited tendency to high blood pressure'. The four nodes for diet, smoking, exercise and inherited tendency all point to a single node labelled 'Raised risk of cardiovascular disease'. That node then points to a final node labelled 'Difficult to prove one factor alone causes the disease'.
    Shows how genetic, lifestyle and environmental factors interact to raise the risk of cardiovascular disease and why a single cause is hard to prove.

    Key words

    Say what each word means before you turn the card.

    Multifactorial disease causation

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    Interaction of genetics, lifestyle and environment

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    Risk assessment and prevention

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    Scientific evidence and causation

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    See every definition
    Multifactorial disease causation
    Many diseases are caused by the interaction of a number of factors rather than a single cause.
    Interaction of genetics, lifestyle and environment
    Factors that can interact include genetics, lifestyle choices and environmental exposures, and together these can raise risk more than any one factor alone.
    Risk assessment and prevention
    Because factors interact, disease prevention is complex, and interacting factors can increase risk more than any single factor alone.
    Scientific evidence and causation
    Because factors interact, it is difficult to prove that one factor alone causes a disease, which makes causal proof complex.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A top-down flowchart. At the top, a node labelled 'Multiple interacting factors' branches into three nodes: 'Genetic factors', 'Lifestyle factors' and 'Environmental factors'. From 'Lifestyle factors' three arrows lead to 'Diet high in saturated fat', 'Smoking' and 'Little exercise'. From 'Genetic factors' one arrow leads to 'Inherited tendency to high blood pressure'. The four nodes for diet, smoking, exercise and inherited tendency all point to a single node labelled 'Raised risk of cardiovascular disease'. That node then points to a final node labelled 'Difficult to prove one factor alone causes the disease'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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