Biology A-Level
methyltransferase and HDAC inhibitors
What methyltransferase and HDAC inhibitors means in Biology A-Level, as defined for AQA.
Definition of methyltransferase and HDAC inhibitors
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Reference: AQA
Drugs that inhibit DNA methyltransferase reduce methylation of tumour suppressor genes so they are expressed again, while histone deacetylase inhibitors increase acetylation, loosening the chromatin and allowing transcription.
Topics that use methyltransferase and HDAC inhibitors
Related terms
- complementary base pairing
- correlation not causation
- decreased histone acetylation
- DNA methylation
- environment and gene expression
- genotype versus environment
- histone acetylation
- hypermethylation of tumour suppressor genes
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