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    Biology GCSE

    Biology GCSE glossary

    43 key terms for Biology GCSE, A to Z, each linked to the topic pages that use it.

    A

    Active Transport
    The movement of substances from a region of lower concentration to a region of higher concentration (against the concentration gradient) using energy from…Pearson Edexcel
    Alveoli
    Tiny air sacs in the lungs adapted for efficient gas exchange.Pearson Edexcel
    Antibody
    A protein produced by lymphocytes that is complementary in shape to a specific antigen, binding to it to neutralise the pathogen.Pearson Edexcel
    Antigen
    A unique protein on the surface of a cell or pathogen that induces an immune response.Pearson Edexcel
    Aseptic technique
    Methods used to prevent contamination by unwanted microorganisms during laboratory experiments.Pearson Edexcel

    B

    Biomass
    The mass of living material in an organism, which represents the chemical energy stored within it.Pearson Edexcel

    C

    Coronary Artery
    The blood vessels that supply the heart muscle tissue itself with oxygenated blood.Pearson Edexcel

    D

    Decomposer
    Microorganisms (bacteria and fungi) that break down dead plant and animal matter by secreting enzymes into the environment.Pearson Edexcel
    Differentiation
    The process by which an unspecialised cell becomes specialised to perform a specific function.Pearson Edexcel
    Diffusion
    The net movement of particles from an area of higher concentration to an area of lower concentration.Pearson Edexcel
    DNA Ligase
    An enzyme used to join the sticky ends of the target gene and the plasmid DNA together.Pearson Edexcel
    Double Circulatory System
    A system where blood passes through the heart twice for every complete circuit of the body.Pearson Edexcel
    Double-blind trial
    A clinical trial where neither the patients nor the doctors know who has been given the real drug and who has been given the placebo.Pearson Edexcel

    E

    Ecosystem
    The interaction of a community of living organisms (biotic) with the non-living (abiotic) parts of their environment.Pearson Edexcel
    Eutrophication
    The hyper-nutrition of a body of water (usually by nitrate fertilisers) leading to algal blooms, oxygen depletion, and death of aquatic life.Pearson Edexcel

    G

    Genetic Modification
    The artificial transfer of a gene from one organism into the genome of another organism.Pearson Edexcel

    H

    Haemoglobin
    The red pigment found in red blood cells that binds reversibly to oxygen.Pearson Edexcel
    Health
    A state of complete physical, mental, and social well-being, and not merely the absence of disease or infirmity.Pearson Edexcel
    Homeostasis
    The regulation of the internal conditions of a cell or organism to maintain optimum conditions for function, in response to internal and external changes.Pearson Edexcel
    Hormone
    A chemical messenger secreted by an endocrine gland directly into the bloodstream, which produces an effect on target organs.Pearson Edexcel

    M

    Mitosis
    A type of cell division that produces two genetically identical diploid daughter cells.Pearson Edexcel
    Mutation
    A random change in the DNA sequence of an organism.Pearson Edexcel
    Myelin Sheath
    A fatty layer surrounding the axon of a neurone that acts as an electrical insulator and speeds up impulse transmission.Pearson Edexcel

    N

    Natural Selection
    The process by which individuals that are better adapted to their environment survive and reproduce, passing on their advantageous alleles.Pearson Edexcel
    Negative Feedback
    A control mechanism that reacts to a change in a condition by trying to bring the condition back to a normal level.Pearson Edexcel
    Nitrifying Bacteria
    Bacteria in the soil that convert ammonium ions into nitrites, and then into nitrates.Pearson Edexcel

    O

    Osmosis
    The net movement of water molecules from a region of higher water potential to a region of lower water potential through a partially permeable membrane.Pearson Edexcel

    P

    Pathogen
    A microorganism that causes infectious disease.Pearson Edexcel
    Phagocytosis
    The process by which white blood cells (phagocytes) engulf and digest pathogens.Pearson Edexcel
    Phototropism
    A plant's growth response to light, controlled by the unequal distribution of auxin.Pearson Edexcel
    Placebo
    A substance that looks exactly like the real medicine but contains no active drug, used as a control in clinical trials.Pearson Edexcel
    Plasma
    The pale yellow liquid component of blood that transports dissolved substances.Pearson Edexcel

    R

    Reflex Action
    A rapid, automatic response to a stimulus that does not involve the conscious part of the brain.Pearson Edexcel
    Reflex Arc
    The nerve pathway involved in a reflex action, bypassing conscious areas of the brain for a faster response.Pearson Edexcel
    Restriction Enzyme
    An enzyme that cuts DNA at a specific sequence, often leaving sticky ends.Pearson Edexcel

    S

    Stem Cell
    An unspecialised cell that can divide and differentiate into different types of specialised cells.Pearson Edexcel
    Stomata
    Tiny pores on the surface of a leaf (usually the lower epidermis) that allow for gas exchange and transpiration.Pearson Edexcel
    Synapse
    The junction between two neurones where chemicals (neurotransmitters) diffuse across the gap to transmit the signal.Pearson Edexcel

    T

    Translocation
    The movement of dissolved sugars and amino acids through the phloem tissue from sources (leaves) to sinks (roots, growing regions).Pearson Edexcel
    Transpiration
    The loss of water vapour from the leaves of a plant, primarily through the stomata.Pearson Edexcel
    Trophic Level
    A specific feeding stage or position within a food chain or food web.Pearson Edexcel
    Type 1 Diabetes
    A disorder in which the pancreas fails to produce sufficient insulin, leading to uncontrolled high blood glucose levels.Pearson Edexcel

    V

    Vector
    An organism that carries and transmits a pathogen to a host without suffering from the disease itself (e.g., a mosquito carrying malaria).Pearson Edexcel

    Where these terms come from

    Each definition is one we publish on a Biology GCSE topic page or study guide. Open a term to see how each exam board words it and which topic it belongs to. For the full course, go to Biology revision or the glossary for every subject.

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