AQA · GCSE · Biology

    Course version: 8461 · Version from Sept 2018

    Stem cells from the embryo are not rejected by the patient’s body so they…

    Full specification wording

    Stem cells: Stem cells from the embryo are not rejected by the patient’s body so they may be used for medical treatment.

    In therapeutic cloning, an embryo is produced with the same genes as the patient.

    Checked against the AQA 8461 specification (opens in a new tab) on .

    • Point 8 of 11

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    In therapeutic cloning, an embryo is produced with the same genes as the patient. Stem cells from this embryo are not rejected by the patient's immune system because they contain the exact same genetic material and therefore the same surface antigens. This makes them highly valuable for medical treatments, as they can differentiate into any type of human cell to replace those lost to disease or injury, such as in diabetes or paralysis. Without therapeutic cloning, donor stem cells might be rejected unless immunosuppressant drugs are used. Understanding this mechanism highlights why these specific embryonic stem cells are so useful in regenerative medicine.

    What earns the marks

    • In therapeutic cloning, an embryo is produced with the same genes as the patient.
    • Stem cells from this embryo are not rejected by the patient's immune system because they share the same genetic material.

    Common mistakes and how to put them right

    • Saying embryonic stem cells are never rejected.

      Put it right by specifying that in therapeutic cloning, they are not rejected because they have the same genes as the patient.

    • Confusing therapeutic cloning with reproductive cloning.

      Put it right by stating therapeutic cloning produces cells for medical treatment, not a new individual.

    • Writing that stem cells themselves treat a disease without explaining differentiation.

      Put it right by stating that they divide and become the needed specialised cells.

    Exam tips

    • Always link the lack of rejection to the fact that the embryo has the same genes as the patient in therapeutic cloning.
    • Use the term differentiate correctly when explaining how stem cells replace damaged cells.

    Try the lesson

    The start of the Stem cells: Stem cells from the embryo are not rejected by the patient’s body so they may be used for medical treatment. lesson, made from checked teaching notes for this specification point.

    Have a go first

    In therapeutic cloning, an embryo is produced with the same genes as the patient. Why are stem cells from this embryo useful for medical treatment?

    Listen

    In therapeutic cloning, an embryo is produced with the same genes as the patient. Stem cells from this embryo are not rejected by the patient's immune system because they contain the exact same genetic material and therefore the same surface antigens. This makes them highly valuable for medical treatments, as they can differentiate into any type of human cell to replace those lost to disease or injury, such as in diabetes or paralysis. Without therapeutic cloning, donor stem cells might be rejected unless immunosuppressant drugs are used. Understanding this mechanism highlights why these specific embryonic stem cells are so useful in regenerative medicine. A strong answer earns marks for these points. In therapeutic cloning, an embryo is produced with the same genes as the patient. Stem cells from this embryo are not rejected by the patient's immune system because they share the same genetic material. A common slip: Saying embryonic stem cells are never rejected. Instead, specifying that in therapeutic cloning, they are not rejected because they have the same genes as the patient. Exam tip: Always link the lack of rejection to the fact that the embryo has the same genes as the patient in therapeutic cloning.

    See it

    A top-down flowchart. The first box reads 'Embryo produced with the same genes as the patient' and points down to a second box, 'Stem cells from this embryo share the patient's genetic material'. This second box branches into two boxes: 'Not rejected by the patient's immune system' and 'Unspecialised stem cells can differentiate into many cell types'. Both of these boxes point to a box reading 'Suitable for medical treatment', which points to a final box reading 'Replacing damaged cells in diabetes or paralysis'.
    It shows how a therapeutically cloned embryo's stem cells share the patient's genes, so they are not rejected and can differentiate, making them suitable for medical treatment.

    Label the diagram

    Some boxes have lost their names. Pick the right name for each number.

    The diagram again, with 3 boxes numbered instead of named. A top-down flowchart. The first box reads 'Embryo produced with the same genes as the patient' and points down to a second box, 'Stem cells from this embryo share the patient's genetic material'. This second box branches into two boxes: 'Not rejected by the patient's immune system' and 'Unspecialised stem cells can differentiate into many cell types'. Both of these boxes point to a box reading 'Suitable for medical treatment', which points to a final box reading 'Replacing damaged cells in diabetes or paralysis'.
    • 1Box 1

    • 2Box 2

    • 3Box 3

    0 of 3 labelled

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